# SIC (Sepsis-Induced Coagulopathy) Score Calculator

> SIC (Sepsis-Induced Coagulopathy) Score Calculator is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).

Computes the Iba 2017 Sepsis-Induced Coagulopathy (SIC) score from platelet count, INR, and partial SOFA score, returning total score and SIC diagnosis flag

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/sic
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/sic-sepsis-induced-coagulopathy-score-calculator-f38c1df7
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_AbxKQ9Rf5b8rlnHTAlc79

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability sic-sepsis-induced-coagulopathy-score-calculator-f38c1df7
```

Example prompt: Can you calculate the SIC score for my ICU patient who has a platelet count of 95 ×10⁹/L, an INR of 1.5, and a combined respiratory plus cardiovascular plus hepatic plus renal SOFA score of 4? I need to know if they meet Iba 2017 SIC criteria.

## When to prefer this

Use this endpoint when you need to apply the Iba 2017 SIC criteria specifically — distinct from ISTH overt DIC, JAAM-DIC, and general sepsis diagnosis. Ideal when you have platelet count, INR, and have already computed the four-organ (respiratory, cardiovascular, hepatic, renal) SOFA subscores and need a fast, rule-based SIC classification without coagulation or CNS SOFA components.

## Known failure modes

- Missing required query parameters (platelets_10e9_l, inr, sofa_four_items) returns a 400 error
- Out-of-range platelet value (outside 1–2000) may return a validation error
- Out-of-range INR (outside 0.8–10) may return a validation error
- sofa_four_items outside integer range 0–16 returns a validation error
- Payment not provided or invalid x402 payment header returns a 402 Payment Required
- Network timeout if the service is temporarily unavailable

## How this service works

Iba 2017 SIC (Table 3; max 6). platelets_10e9_l >=150=0, <150 and >=100=1, <100=2. inr <=1.2=0, >1.2 and <=1.4=1, >1.4=2. sofa_four_items is the caller-assigned respiratory+cardiovascular+hepatic+renal SOFA sum (0-16; not coagulation, not CNS): 0=0, 1=1, >=2=2 (cap 2). sic true iff score >=4 and platelet_pts+inr_pts >=3. Not a sepsis or DIC diagnosis. Not ISTH overt DIC. Not JAAM-DIC. magent does not start anticoagulants.

## Output

Returns the total SIC score (0–6), individual component points for platelets (0–2), INR (0–2), and the capped SOFA contribution (0–2), plus a boolean SIC-positive flag (true if total score ≥4 AND platelet_pts + INR_pts ≥3). Does not initiate treatment or provide a DIC or sepsis diagnosis.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "platelets_10e9_l",
      "inr",
      "sofa_four_items"
     ],
     "properties": {
      "inr": {
       "type": "number",
       "description": "INR (0.8-10). <=1.2 scores 0; >1.2 and <=1.4 scores 1; >1.4 scores 2. 1.2 scores 0; 1.4 scores 1; 1.41 scores 2 (Iba 2017 Table 3)."
      },
      "sofa_four_items": {
       "type": "integer",
       "description": "Caller-assigned sum of respiratory + cardiovascular + hepatic + renal SOFA only (integer 0-16). Do not include coagulation or CNS. 0 scores 0; 1 scores 1; >=2 scores 2 (cap 2). 2 and 16 both score 2 (Iba 2017 Table 3). magent does not compute those organ scores."
      },
      "platelets_10e9_l": {
       "type": "number",
       "description": "Platelet count ×10^9/L (1-2000). >=150 scores 0; <150 and >=100 scores 1; <100 scores 2. 150 scores 0; 100 scores 1; 99 scores 2 (Iba 2017 Table 3)."
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/sic-sepsis-induced-coagulopathy-score-calculator-f38c1df7/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)