# SIRS Criteria Calculator (Bone 1992 ACCP/SCCM)

> SIRS Criteria Calculator (Bone 1992 ACCP/SCCM) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-10-12).

Calculates Systemic Inflammatory Response Syndrome (SIRS) score using the classic Bone 1992 ACCP/SCCM four-criterion definition, returning whether SIRS is present (≥2 of 4 criteria met).

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/sirs?utm_source=zero.xyz
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-12
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/sirs-criteria-calculator-bone-1992-accp-sccm-9250da43
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_JgU_wAPd_K-AJqR0RjlSG

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability sirs-criteria-calculator-bone-1992-accp-sccm-9250da43
```

Example prompt: Does this patient meet SIRS criteria? Temperature is 38.5 °C, heart rate is 102 bpm, respiratory rate is 22 breaths/min, and WBC is 14,500 per µL.

## When to prefer this

Use this endpoint when you need a fast, deterministic, citation-backed SIRS calculation per the original Bone 1992 ACCP/SCCM definition. Prefer it over manual rule-coding when building clinical decision support, sepsis screening pipelines, or automated chart review tools. Note this is NOT Sepsis-3, qSOFA, or SOFA — choose it explicitly when the older SIRS framework is required (e.g., for legacy protocols, research replication, or insurance/billing workflows referencing Bone 1992).

## Known failure modes

- Missing required parameters (temperature_c, heart_rate_bpm, respiratory_rate) returns a 400 error
- Temperature out of range 30.0–45.0 °C rejected
- Heart rate outside 30–220 bpm rejected
- Respiratory rate outside 4–80 rejected
- WBC value out of accepted range rejected
- Payment not included or invalid returns 402 Payment Required
- Providing both wbc_ul and wbc_k_ul may cause ambiguity — prefer one unit

## How this service works

Deterministic published-formula arithmetic plus ICD-10-CM, RxNorm, and LOINC. Pay in USDC on Base via x402.

## Output

Returns a structured object indicating whether SIRS is present (true/false), the total number of SIRS criteria met (0–4), and the individual pass/fail result for each of the four criteria: temperature, heart rate, respiratory/PaCO2, and WBC/bands.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "temperature_c",
      "heart_rate_bpm",
      "respiratory_rate"
     ],
     "properties": {
      "wbc_ul": {
       "type": "number",
       "description": "WBC in cells/µL (same as cells/mm^3). Provide wbc_k_ul or wbc_ul. Range 10-500000. >12000 or <4000 scores 1 (12000 and 4000 do not)."
      },
      "wbc_k_ul": {
       "type": "number",
       "description": "WBC in 10^3/µL (same as 10^9/L). Provide wbc_k_ul or wbc_ul. Range 0.01-500. >12000 or <4000 per µL scores 1."
      },
      "paco2_mm_hg": {
       "type": "number",
       "description": "Arterial PaCO2 in mm Hg (8-80) when provided. Omitted uses respiratory rate only. <32 scores the respiratory criterion (32 does not)."
      },
      "band_percent": {
       "type": "number",
       "description": "Immature bands as a percent of WBC (0-100) when provided. Omitted does not use bands. >10 scores the WBC criterion (10 does not)."
      },
      "temperature_c": {
       "type": "number",
       "description": "Temperature in °C (30.0-45.0). >38 or <36 scores 1 (38.0 and 36.0 do not)."
      },
      "heart_rate_bpm": {
       "type": "integer",
       "description": "Heart rate in beats/min (integer 30-220). >90 scores 1 (90 does not)."
      },
      "respiratory_rate": {
       "type": "integer",
       "description": "Respiratory rate in breaths/min (integer 4-80). >20 scores 1 for the respiratory criterion (20 does not). Optional paco2_mm_hg <32 also meets this criterion."
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "path": "/api/calc/sirs",
  "count": 2,
  "items": [
   {
    "formula": "sirs",
    "citation": {
     "id": "bone-1992",
     "doi": "10.1378/chest.101.6.1644",
     "title": "Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis",
     "source": "Chest. 1992;101(6):1644-1655",
     "authors": "Bone RC, Balk RA, Cerra FB, et al."
    },
    "max_score": 4,
    "components": [
     {
      "value": 37,
      "factor": "temperature",
      "points": 0,
      "present": false
     },
     {
      "value": 80,
      "factor": "heart_rate_gt_90",
      "points": 0,
      "present": false
     },
     {
      "value": 16,
      "factor": "respiratory",
      "points": 0,
      "present": false
     },
     {
      "value": 8000,
      "factor": "wbc",
      "points": 0,
      "present": false
     }
    ],
    "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
    "wbc_per_ul": 8000,
    "sirs_present": false,
    "temperature_c": 37,
    "heart_rate_bpm": 80,
    "respiratory_rate": 16,
    "sirs_criteria_met": 0,
    "formula_expression": "SIRS present iff >=2 of 4: (temperature_c >38 or <36) + (heart_rate_bpm >90) + (respiratory_rate >20 or paco2_mm_hg <32) + (wbc_per_ul >12000 or <4000 or band_percent >10); each 1; max 4"
   },
   {
    "formula": "sirs",
    "citation": {
     "id": "bone-1992",
     "doi": "10.1378/chest.101.6.1644",
     "title": "Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis",
     "source": "Chest. 1992;101(6):1644-1655",
     "authors": "Bone RC, Balk RA, Cerra FB, et al."
    },
    "max_score": 4,
    "components": [
     {
      "value": 37,
      "factor": "temperature",
      "points": 0,
      "present": false
     },
     {
      "value": 80,
      "factor": "heart_rate_gt_90",
      "points": 0,
      "present": false
     },
     {
      "value": 16,
      "factor": "respiratory",
      "points": 0,
      "present": false
     },
     {
      "value": 8000,
      "factor": "wbc",
      "points": 0,
      "present": false
     }
    ],
    "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
   
… (truncated)
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/sirs-criteria-calculator-bone-1992-accp-sccm-9250da43/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)