# SiteCheck FDA Adverse Events Lookup

> SiteCheck FDA Adverse Events Lookup is a paid API for AI agents from api.sitecheck-api.workers.dev, paid per call via x402, $0.002/call, status unknown (last checked 2026-10-28).

Returns the top adverse event reactions reported to the FDA for a given drug, sourced from the openFDA FAERS database.

## Facts

- Endpoint: GET https://api.sitecheck-api.workers.dev/api/fda/adverse-events?utm_source=zero.xyz
- Price: $0.002/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-28
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/sitecheck-fda-adverse-events-lookup-eb57b879
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_HXTbORyNwjDYZH-Ppir0k

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability sitecheck-fda-adverse-events-lookup-eb57b879
```

Example prompt: What are the top 10 adverse events reported to the FDA for ibuprofen? Pull the data from the FDA FAERS database and show me how many reports are serious.

## When to prefer this

Use this endpoint when you need quick, aggregated FDA FAERS adverse event statistics for a named drug without building your own openFDA integration. It's ideal for AI agents performing drug safety lookups, pharmacovigilance summaries, or healthcare compliance checks. Prefer it over direct openFDA calls when you want pay-per-call simplicity with pre-aggregated reaction counts and seriousness metrics already computed.

## Known failure modes

- Drug name not found in FAERS — returns empty reactions array or error
- Invalid or missing 'drug' query parameter — likely 400 or error response
- Limit parameter outside 1–25 range — may default or return error
- OpenFDA upstream API unavailable — proxy error or timeout
- Misspelled drug name yields no results or unexpected matches

## How this service works

The most reported adverse reactions to a drug in FDA's FAERS database: counts, total reports and the share that were serious. Reports are voluntary and show association, not proof of cause. Source: openFDA. Information only, not medical advice.

## Output

A JSON object containing the queried drug name, the openFDA source URL, a timestamp, an ordered list of up to 25 adverse reactions each with their report count, total report count, serious report count, serious share percentage, and disclaimers about data provenance (FAERS, not proof of causation).

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "required": [
      "drug"
     ],
     "properties": {
      "drug": {
       "type": "string",
       "description": "Generic drug name, e.g. ibuprofen"
      },
      "limit": {
       "type": "string",
       "description": "Top reactions, 1 to 25 (default 10)"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "drug": "ibuprofen",
  "source": "https://api.fda.gov/drug/event.json",
  "checkedAt": "2026-10-14T07:00:32.179Z",
  "reactions": [
   {
    "reports": 27383,
    "reaction": "DRUG INEFFECTIVE"
   },
   {
    "reports": 19493,
    "reaction": "PAIN"
   },
   {
    "reports": 18755,
    "reaction": "FATIGUE"
   }
  ],
  "disclaimer": "Information only, not medical advice.",
  "attribution": "openFDA (FAERS, reports are not proof of cause)",
  "totalReports": 283534,
  "seriousReports": 178866,
  "seriousSharePct": 63.1
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/sitecheck-fda-adverse-events-lookup-eb57b879/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.sitecheck-api.workers.dev](https://www.zero.xyz/host/api.sitecheck-api.workers.dev/llms.txt)