# SLICC 2012 SLE Classifier

> SLICC 2012 SLE Classifier is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).

Applies the SLICC 2012 classification criteria to determine if a patient meets the definition of systemic lupus erythematosus (SLE), including the biopsy-proven lupus nephritis shortcut.

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/slicc_sle
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-15
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/slicc-2012-sle-classifier-fd662dd0
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_XgfxTD0VWgTeAS84vztVC

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability slicc-2012-sle-classifier-fd662dd0
```

Example prompt: Apply the SLICC 2012 SLE classification to my patient: they have synovitis, serositis, and nonscarring alopecia as clinical findings, and ANA and low complement as immunologic findings — no biopsy-proven lupus nephritis, no hemolytic anemia, no direct Coombs issue. Do they meet SLICC 2012 criteria?

## When to prefer this

Use this endpoint when you need to apply the specific SLICC 2012 (Petri Table 3) classification framework for SLE — not the 1997 ACR criteria and not the 2019 EULAR/ACR criteria. Ideal for clinical decision support pipelines, research cohort screening, or EHR-integrated tools where clinical and immunologic assessments have already been made by a clinician and need to be scored automatically. Do not use if you need the 1997 ACR or 2019 EULAR/ACR classification.

## Known failure modes

- Missing required query parameters (all 18 Boolean flags are required) returns a validation error
- Passing non-Boolean values for flag parameters causes a schema error
- Misinterpreting the direct Coombs flag: it only counts in the absence of hemolytic anemia — the caller must enforce this logic before passing values
- Confusing the renal clinical criterion with biopsy_lupus_nephritis — these are distinct parameters
- Expecting the API to perform lab assays, physical examination, or biopsy reading — it only scores caller-supplied flags

## How this service works

SLICC 2012 SLE classification (Petri Table 3). classified iff biopsy-proven lupus nephritis plus ANA or anti-dsDNA, or at least four criteria including at least one clinical and one immunologic. 11 clinical and 6 immunologic caller flags. Direct Coombs counts only in the absence of hemolytic anemia. Criteria need not be concurrent. Not a diagnosis. Not 1997 ACR. Not 2019 EULAR/ACR. magent does not examine skin, assay serologies, or read a biopsy.

## Output

A structured result indicating whether the patient meets the SLICC 2012 SLE classification criteria, including whether the biopsy-proven lupus nephritis shortcut was triggered, how many clinical and immunologic criteria were satisfied, and whether the minimum four-criterion threshold (with at least one clinical and one immunologic) was reached. This is a classification output, not a clinical diagnosis.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "acute_cutaneous_lupus",
      "chronic_cutaneous_lupus",
      "oral_or_nasal_ulcers",
      "nonscarring_alopecia",
      "synovitis",
      "serositis",
      "renal",
      "neurologic",
      "hemolytic_anemia",
      "leukopenia_or_lymphopenia",
      "thrombocytopenia",
      "ana",
      "anti_dsdna",
      "anti_sm",
      "antiphospholipid",
      "low_complement",
      "direct_coombs",
      "biopsy_lupus_nephritis"
     ],
     "properties": {
      "ana": {
       "type": "boolean",
       "description": "ANA above laboratory reference range as assigned by the caller (Petri 2012 Table 3). With biopsy_lupus_nephritis (or anti_dsdna), fulfills the nephritis shortcut. true or false. magent does not assay ANA."
      },
      "renal": {
       "type": "boolean",
       "description": "Renal clinical criterion as assigned by the caller (Petri 2012 Table 3): urine protein-to-creatinine ratio (or 24-hour urine protein) representing 500 mg protein/24 hours, or red blood cell casts. Distinct from biopsy_lupus_nephritis. true or false. magent does not assay urine."
      },
      "anti_sm": {
       "type": "boolean",
       "description": "Antibody to Sm nuclear antigen as assigned by the caller (Petri 2012 Table 3). true or false. magent does not assay anti-Sm."
      },
      "serositis": {
       "type": "boolean",
       "description": "Serositis as assigned by the caller (Petri 2012 Table 3): typical pleurisy >1 day or pleural effusion or pleural rub, or typical pericardial pain >1 day or pericardial effusion or pericardial rub or pericarditis by electrocardiography, in the absence of other causes. true or false. magent does not examine the chest."
      },
      "synovitis": {
       "type": "boolean",
       "description": "Synovitis involving 2 or more joints, characterized by swelling or effusion, or tenderness in 2 or more joints and at least 30 minutes of morning stiffnes
… (truncated)
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/slicc-2012-sle-classifier-fd662dd0/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)
