# Suverse Bio Ensembl Gene Lookup

> Suverse Bio Ensembl Gene Lookup is a paid API for AI agents from proxy.suverse.io, paid per call via x402, $0.002/call, status unknown (last checked 2026-09-14).

Resolves a human gene HGNC symbol to Ensembl genomic annotations including gene ID, biotype, chromosome, coordinates, strand, and genome assembly.

## Facts

- Endpoint: POST https://proxy.suverse.io/v1/data/suverse-bio-ensembl-gene-lookup
- Price: $0.002/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/suverse-bio-ensembl-gene-lookup-61597c96
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_8cj_O6V9vFajmsXQIEugt

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability suverse-bio-ensembl-gene-lookup-61597c96 -d '<json body>'
```

Example prompt: Look up the Ensembl annotation for the human gene BRCA1 — I need the Ensembl gene ID, biotype, chromosome, start and end coordinates, strand, and genome assembly.

## When to prefer this

Choose this endpoint when an agent needs keyless, pay-per-call access to Ensembl gene annotations without managing API keys or rate limits. It is ideal for bioinformatics pipelines, genomic data enrichment workflows, or any agent that needs to resolve HGNC gene symbols to stable Ensembl IDs and coordinates on demand. Prefer it over direct Ensembl REST calls when operating in an x402 payment-gated agentic environment.

## Known failure modes

- Unrecognized or misspelled HGNC symbol returns empty results or error
- Gene symbol that maps to multiple Ensembl entries may return ambiguous results
- Non-human gene symbols are not supported and will fail
- Ensembl REST backend outage causes upstream timeout
- Deprecated or retired gene symbols may not resolve correctly

## How this service works

Look up a human gene by HGNC symbol in Ensembl; returns Ensembl gene ID, biotype, chromosome, coordinates, strand, and assembly. Keyless Ensembl REST. For agents resolving gene symbols to genomic annotations.

## Output

Returns structured genomic annotations for the queried HGNC gene symbol, including: Ensembl gene ID (e.g. ENSG00000012048), biotype (e.g. protein_coding, lncRNA), chromosome name, genomic start and end coordinates, strand orientation (+1 or -1), and reference genome assembly version (e.g. GRCh38).

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method",
    "bodyType",
    "body"
   ],
   "properties": {
    "body": {
     "properties": {}
    },
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "POST",
      "PUT",
      "PATCH"
     ],
     "type": "string"
    },
    "bodyType": {
     "enum": [
      "json",
      "form-data",
      "text"
     ],
     "type": "string"
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/suverse-bio-ensembl-gene-lookup-61597c96/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from proxy.suverse.io](https://www.zero.xyz/host/proxy.suverse.io/llms.txt)