# Synapse Clinical Trials Search

> Synapse Clinical Trials Search is a paid API for AI agents from anibalb.duckdns.org, paid per call via x402, $0.002/call, status unknown (last checked 2026-10-31).

Returns a list of clinical trials including NCT ID, phase, title, study type, lead sponsor, and recruitment status

## Facts

- Endpoint: GET https://anibalb.duckdns.org/x402/clinical-trials?utm_source=zero.xyz
- Price: $0.002/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-31
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/synapse-clinical-trials-search-2c6c220d
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_fp0iAmqdvYgUhuPgHyH63

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability synapse-clinical-trials-search-2c6c220d
```

Example prompt: Can you pull a list of clinical trials that are currently recruiting, especially any Phase 2 interventional studies? I want to see the NCT IDs, sponsors, and their current status.

## When to prefer this

Choose this endpoint when you need quick, pay-per-call access to clinical trial data without setting up API keys or accounts. It is ideal for agents needing to programmatically query ClinicalTrials.gov data via a micropayment model on Base using USDC. Prefer alternatives (direct ClinicalTrials.gov API) if you need advanced filtering, full trial details, or high-volume queries where per-call pricing becomes expensive.

## Known failure modes

- Payment failure via x402 protocol returns 402 with payment instructions
- No trials found returns count:0 and empty trials array
- Network timeout if upstream ClinicalTrials.gov is slow
- Malformed query parameters may return empty or error response
- DuckDNS domain may have intermittent availability

## How this service works

Public data and utility APIs paid per call in USDC on Base (x402). No accounts, no API keys. 174 routes: crypto/equity data, onchain reads, DNS/email/security intel, geo/weather, x402 payment diagnostics, dev utilities and more.

## Output

Returns a JSON object with a count of matching trials and an array of trial objects, each containing: NCT ID, phase (e.g. PHASE2), title, study type (e.g. INTERVENTIONAL), lead sponsor name, and overall status (e.g. RECRUITING).

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {}
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "count": 2,
  "trials": [
   {
    "nctId": "NCT07839429",
    "phase": [
     "PHASE2"
    ],
    "title": "...",
    "studyType": "INTERVENTIONAL",
    "leadSponsor": "...",
    "overallStatus": "RECRUITING"
   }
  ]
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/synapse-clinical-trials-search-2c6c220d/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from anibalb.duckdns.org](https://www.zero.xyz/host/anibalb.duckdns.org/llms.txt)