# SYNTHORA openFDA Drug Adverse Event Reports (FAERS)

> SYNTHORA openFDA Drug Adverse Event Reports (FAERS) is a paid API for AI agents from openfda-drug-adverse-events.hergertsynthora.com, paid per call via x402, $0.001/call, status unknown (last checked 2026-09-14).

Queries the FDA Adverse Event Reporting System (FAERS) via openFDA to return patient adverse reactions, suspect drugs, seriousness, outcomes, dosing, and demographics for a given medicinal product.

## Facts

- Endpoint: POST https://openfda-drug-adverse-events.hergertsynthora.com/service
- Price: $0.001/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/synthora-openfda-drug-adverse-event-reports-faers-4cbbefbf
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_KP1vvyU-BjFr5fx9FCO0p

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability synthora-openfda-drug-adverse-event-reports-faers-4cbbefbf -d '<json body>'
```

Example prompt: Pull the top 10 FDA FAERS adverse event case reports for metformin — I want to see the patient reactions, seriousness flags, and outcomes reported.

## When to prefer this

Choose this endpoint when you need structured FAERS adverse event data from openFDA without managing the openFDA API directly — particularly suited for autonomous pharmacovigilance agents, drug safety signal detection pipelines, and risk-scoring systems that need to query adverse event frequency and reaction data for a specific medicinal product at low cost per call.

## Known failure modes

- Invalid or malformed search query returns no results or openFDA error
- Drug name not found in FAERS database returns empty result set
- Limit parameter out of bounds may return unexpected result counts
- openFDA upstream API downtime causes service unavailability
- Overly broad search queries may exceed rate limits or return truncated data

## How this service works

Returns FDA Adverse Event Reporting System (FAERS) case reports from openFDA api.fda.gov/drug/event: patient reactions (MedDRA terms), suspect drugs, seriousness, outcomes, dose and demographics for a given medicinal product. Autonomous agents and agent-to-agent (A2A) pharmacovigilance, drug-safety-signal and risk-scoring systems mine it to surface adverse-event frequency. Ranking surface: drug name to reaction counts.

## Output

Returns a JSON object with an 'ok' flag and a 'result' object containing FAERS case reports sourced from openFDA, including MedDRA patient reaction terms, suspect drug details, seriousness indicators, patient outcomes, dosage information, and demographic data for the queried drug.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "properties": {
  "limit": {
   "type": "integer",
   "description": "limit"
  },
  "search": {
   "type": "string",
   "description": "search"
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "ok": true,
  "niche": "openfda-drug-adverse-events",
  "result": {}
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/synthora-openfda-drug-adverse-event-reports-faers-4cbbefbf/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from openfda-drug-adverse-events.hergertsynthora.com](https://www.zero.xyz/host/openfda-drug-adverse-events.hergertsynthora.com/llms.txt)