# UniRef Protein Sequence Cluster Search

> UniRef Protein Sequence Cluster Search is a paid API for AI agents from clonecho.builda.company, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-14).

Search UniRef protein sequence clusters by keyword and return matching cluster metadata as JSON.

## Facts

- Endpoint: POST https://clonecho.builda.company/x402/s/uniprot-uniref-search
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/uniref-protein-sequence-cluster-search-d4b1108f
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_5e22KgJGPuNn-k8FW-Hb5

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability uniref-protein-sequence-cluster-search-d4b1108f -d '<json body>'
```

Example prompt: Search UniRef protein sequence clusters for 'hemoglobin' and give me the matching cluster records.

## When to prefer this

Use this endpoint when you need to search the UniRef protein sequence cluster database by keyword — ideal for bioinformatics workflows requiring cluster-level protein family lookups, homology grouping, or representative sequence retrieval. Prefer over direct UniProt search when cluster-level granularity (e.g. UniRef50/90/100) is needed.

## Known failure modes

- Missing or empty query parameter returns error or empty result set
- Ambiguous keyword returns too many or irrelevant clusters
- Misspelled protein name yields no results
- Service unavailable or payment failure returns HTTP 402 or 5xx
- Rate limiting if called too frequently

## How this service works

Search UniRef protein sequence clusters by keyword {q}. Query: ?q= Returns JSON.

## Output

A JSON array or object containing UniRef cluster records matching the keyword, including cluster IDs, names, representative sequences, organism taxonomy, and member counts.

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/uniref-protein-sequence-cluster-search-d4b1108f/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from clonecho.builda.company](https://www.zero.xyz/host/clonecho.builda.company/llms.txt)