# Vextorium Clinical Trials Search

> Vextorium Clinical Trials Search is a paid API for AI agents from api.vextorium.com, paid per call via x402, $0.003/call, status unknown (last checked 2026-10-19).

Searches ClinicalTrials.gov for clinical trials by disease, drug, or sponsor, returning detailed trial metadata including NCT ID, status, phase, conditions, interventions, and enrollment.

## Facts

- Endpoint: POST https://api.vextorium.com/v1/clinical-trials?utm_source=zero.xyz
- Price: $0.003/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-19
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/vextorium-clinical-trials-search-4f47e8f2
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_bHMpQRo2qiRpHZ_lql_Je

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability vextorium-clinical-trials-search-4f47e8f2 -d '<json body>'
```

Example prompt: Can you find recruiting clinical trials for GLP-1 drugs targeting obesity? Show me up to 20 results including their NCT IDs, phases, sponsors, and which countries they're running in.

## When to prefer this

Use this endpoint when you need structured, queryable clinical trial data from ClinicalTrials.gov without building a direct NIH API integration. It is especially useful for agents doing medical research, competitive pharmaceutical intelligence, or patient-facing trial matching, and when you need recruiting trials by default with clean structured output. Prefer this over raw ClinicalTrials.gov API access when you need normalized, ready-to-use JSON with enrollment and country data already parsed.

## Known failure modes

- Empty results if search term is too specific or misspelled
- Null fields for trials missing optional metadata (phases, countries, expected_end)
- Status filter returning no results if no trials match the requested status
- Rate limiting or payment failure if USDC balance is insufficient
- Malformed search string causing backend query failure

## How this service works

558 pay-per-call data APIs for AI agents: Solana and EVM on-chain data, tokenized stocks, DeFi, Hyperliquid, economy and official statistics, FX, validation, web and developer tools. Pay in USDC via x402.

## Output

Returns a JSON object with total match count, search term echoed back, data source attribution, and an array of trial objects. Each trial includes: NCT ID, direct ClinicalTrials.gov link, title, current status, phase(s), sponsoring organization, medical conditions studied, interventions tested, start date, expected end date, participant count, and countries where the trial runs.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "properties": {
  "limit": {
   "type": "integer"
  },
  "search": {
   "type": "string"
  },
  "status": {
   "enum": [
    "recruiting",
    "active",
    "completed",
    "all"
   ],
   "type": "string"
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "total": 247,
  "search": "GLP-1 obesity",
  "source": "ClinicalTrials.gov (NIH/NLM, EE. UU.)",
  "status": "recruiting",
  "trials": [
   {
    "nct": "NCT07065552",
    "link": "https://clinicaltrials.gov/study/NCT07065552",
    "start": "2026-04-27",
    "title": "Tirzepatide in Obesity-Driven Endometrial Cancer",
    "phases": [
     "EARLY_PHASE1"
    ],
    "status": "RECRUITING",
    "sponsor": "UNC Lineberger Comprehensive Cancer Center",
    "countries": [
     "United States"
    ],
    "conditions": [
     "Endometrial Cancer",
     "Obesity"
    ],
    "expected_end": "2028-07",
    "participants": 20,
    "interventions": [
     "Tirzepatide"
    ]
   },
   {
    "nct": "NCT07853898",
    "link": "https://clinicaltrials.gov/study/NCT07853898",
    "start": "2026-10",
    "title": "Effects of Pistachios on Postprandial Metabolic Responses in Adults With Overweight or Obesity",
    "phases": [
     "NA"
    ],
    "status": "RECRUITING",
    "sponsor": "St. Louis University",
    "countries": [
     "United States"
    ],
    "conditions": [
     "Obesity / Overweight"
    ],
    "expected_end": "2027-07",
    "participants": 28,
    "interventions": [
     "Pistachio Co-consumption",
     "Refined-Carbohydrate Control Co-consumption"
    ]
   }
  ]
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/vextorium-clinical-trials-search-4f47e8f2/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.vextorium.com](https://www.zero.xyz/host/api.vextorium.com/llms.txt)