# Vextorium PubMed Search

> Vextorium PubMed Search is a paid API for AI agents from api.vextorium.com, paid per call via x402, $0.003/call, status unknown (last checked 2026-10-19).

Searches PubMed (NCBI/NLM) for biomedical and life sciences research articles by keyword query, with optional result limit and date filtering.

## Facts

- Endpoint: POST https://api.vextorium.com/v1/pubmed-search?utm_source=zero.xyz
- Price: $0.003/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-19
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/vextorium-pubmed-search-f3ada81f
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_P5-0a3qroG2t1VSgt9Odv

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability vextorium-pubmed-search-f3ada81f -d '<json body>'
```

Example prompt: Search PubMed for the latest research on CRISPR cancer therapy — return the top 10 articles published since 2023, including titles, authors, journals, and abstracts.

## When to prefer this

Use this endpoint when an agent needs to search the authoritative biomedical literature database (PubMed/NCBI) for peer-reviewed scientific articles, with structured metadata including abstracts, DOIs, and author lists. It is ideal for research assistants, medical AI workflows, drug discovery pipelines, or any agent task requiring access to life sciences publications. Prefer this over general web search when the user specifically wants indexed academic journal articles from PubMed rather than broader web content.

## Known failure modes

- Empty or overly broad query returns large result sets that may be truncated
- Very narrow or misspelled queries return zero articles
- since_year filter with future year or invalid integer may return no results
- Rate limits or upstream PubMed API downtime may cause failures
- Limit values exceeding backend caps may be silently clamped

## How this service works

Search biomedical literature indexed in PubMed, via OpenAlex (CC0): title, authors, journal, date, DOI, PMID, citation count and open-access link, newest first, with optional year filter. Metadata only (no abstracts).

## Output

Returns a JSON object containing the original query string, total number of matching records in PubMed, the source label ('PubMed (NCBI/NLM)'), and an array of article objects — each with title, list of authors, journal name, publication date, abstract summary, DOI, PMID, and a direct PubMed URL link.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "properties": {
  "limit": {
   "type": "integer"
  },
  "query": {
   "type": "string"
  },
  "since_year": {
   "type": "integer"
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "note": "Metadata only (no abstracts, whose rights belong to the publishers).",
  "query": "crispr cancer",
  "total": 115662,
  "source": "OpenAlex (data released under CC0)",
  "articles": [
   {
    "doi": "10.36721/pjps.2026.39.12.346.1",
    "date": "2026-12-01",
    "link": "https://pubmed.ncbi.nlm.nih.gov/42708786/",
    "pmid": "42708786",
    "title": "Therapeutic efficacy of naloxone hydrochloride combined with hemoperfusion in toxic acute renal failure via the oxidative stress/Nrf2 pathway.",
    "authors": [
     "Yin Zhu",
     "Huichun Sun"
    ],
    "journal": "PubMed",
    "citations": 0,
    "open_access": null
   },
   {
    "doi": "10.1080/03630269.2026.2725724",
    "date": "2026-10-15",
    "link": "https://pubmed.ncbi.nlm.nih.gov/42876272/",
    "pmid": "42876272",
    "title": "Precision Medicine in Sickle Cell Disease: From Molecular Pathways to Curative Strategies",
    "authors": [
     "Dina Tluli",
     "Omar Tluli"
    ],
    "journal": "Hemoglobin",
    "citations": 0,
    "open_access": "https://www.tandfonline.com/doi/pdf/10.1080/03630269.2026.2725724?needAccess=true"
   }
  ]
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/vextorium-pubmed-search-f3ada81f/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.vextorium.com](https://www.zero.xyz/host/api.vextorium.com/llms.txt)