# X402-NVIDIA ESMFold Protein Structure Prediction

> X402-NVIDIA ESMFold Protein Structure Prediction is a paid API for AI agents from x402-nvidia.vercel.app, paid per call via x402, $0.055091/call, status unknown (last checked 2026-09-14).

Predicts 3D protein structure from amino acid sequence using NVIDIA NIM's ESMFold model, paid via x402 micropayments

## Facts

- Endpoint: POST https://x402-nvidia.vercel.app/api/esmfold
- Price: $0.055091/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/x402-nvidia-esmfold-protein-structure-prediction-f35142ba
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_25bKGaEmghXnjyO95irlF

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability x402-nvidia-esmfold-protein-structure-prediction-f35142ba -d '<json body>'
```

Example prompt: Predict the 3D folded structure of this protein sequence using ESMFold: MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGAEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLELEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQAGVWPAAVRESVPSLL

## When to prefer this

Use this endpoint when you need fast, AI-based protein structure prediction from a raw amino acid sequence without setting up local ESMFold infrastructure; ideal for one-off predictions billed per call via USDC micropayments rather than subscription

## Known failure modes

- Invalid or malformed amino acid sequence returns error
- Sequence too long for model context window
- Payment authorization failure via x402 protocol
- NVIDIA NIM backend timeout for complex sequences
- Empty or missing sequence input

## How this service works

Access 48+ NVIDIA NIM AI models via x402 micropayments. Chat completions, vision, safety, translation, and more.

## Output

Returns a predicted protein 3D structure including atomic coordinates, confidence scores (pLDDT), and potentially PDB-format output representing the folded conformation of the input amino acid sequence

## Response schema (JSON Schema)

```json
{
 "type": "object",
 "example": {
  "choices": [
   {
    "message": {
     "role": "assistant",
     "content": "Hello!"
    }
   }
  ]
 },
 "properties": {
  "choices": {
   "type": "array",
   "description": "Model responses"
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/x402-nvidia-esmfold-protein-structure-prediction-f35142ba/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from x402-nvidia.vercel.app](https://www.zero.xyz/host/x402-nvidia.vercel.app/llms.txt)