# Zisman 2002 Localized N0M0 UISS Risk Classifier (RCC)

> Zisman 2002 Localized N0M0 UISS Risk Classifier (RCC) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-10-16).

Stratifies surgically resected, node-negative, metastasis-free unilateral renal cell carcinoma into low, intermediate, or high risk using the Zisman 2002 localized UISS model (pathological T-stage, Fuhrman grade, ECOG)

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/uiss?utm_source=zero.xyz
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-16
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/zisman-2002-localized-n0m0-uiss-risk-classifier-rcc-dc9163ee
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_xpEdz2wKCoTDKkgIX-Rir

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability zisman-2002-localized-n0m0-uiss-risk-classifier-rcc-dc9163ee
```

Example prompt: Using the Zisman 2002 localized UISS model, what's the risk group for a patient with pathological T-stage t3, Fuhrman grade 3, ECOG performance status 1, and confirmed N0M0 disease after surgical resection?

## When to prefer this

Use this endpoint when you need the Zisman 2002 localized (N0M0) UISS risk group specifically — i.e. the three-tier stratification (low/intermediate/high) for surgically resected, node-negative, metastasis-free unilateral RCC using 1997 pathological T-stage, Fuhrman grade 1-4, and ECOG 0-4. Do not use for metastatic UISS, 2001 Roman-numeral I-V staging, SSIGN score, or any case where N or M status is positive. Prefer this over manual lookup tables when integrating risk stratification into clinical workflows or oncology dashboards.

## Known failure modes

- n0_m0 set to false — endpoint is out of scope for node-positive or metastatic disease
- fuhrman_grade outside integer range 1-4 (e.g. 0, 5, or non-integer) — rejected
- ecog value of 5 (deceased) — not scored, rejected
- t_stage not one of t1/t2/t3/t4 — enum validation failure
- metastatic UISS or 2001 I-V staging requested — wrong endpoint
- missing required query parameters — request rejected

## How this service works

Zisman 2002 localized N0M0 UISS for surgically resected unilateral RCC. Caller-assigned 1997 pathological T (t1-t4), Fuhrman 1-4, ECOG 0-4, and n0_m0 true. Returns low_risk (T1, Fuhrman 1-2, ECOG 0), high_risk (T3 with Fuhrman 2-4 and ECOG ≥1, or any T4), or intermediate_risk (every other N0M0 combination). Not 2001 I-V. Not metastatic UISS. Not SSIGN. magent does not assign TNM or read slides. Not a diagnosis. Not a medical device.

## Output

Returns one of three risk classifications: low_risk (T1 with Fuhrman grade 1-2 and ECOG 0), high_risk (T3 with Fuhrman 2-4 and ECOG ≥1, or any T4), or intermediate_risk (all other N0M0 combinations meeting the eligibility criteria).

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "t_stage",
      "n0_m0",
      "fuhrman_grade",
      "ecog"
     ],
     "properties": {
      "ecog": {
       "type": "integer",
       "description": "Oken 1982 ECOG performance status 0-4 as assigned by the caller. Grade 5 (dead) is not scored. magent does not observe the patient."
      },
      "n0_m0": {
       "type": "boolean",
       "description": "Must be true: surgically resected unilateral RCC that is node-negative and metastasis-negative (Zisman 2002 localized N0M0 UISS). N-positive or M-positive disease is out of scope. Not metastatic UISS."
      },
      "t_stage": {
       "enum": [
        "t1",
        "t2",
        "t3",
        "t4"
       ],
       "type": "string",
       "description": "1997 pathological T as assigned by the caller (Zisman 2002 localized UISS). t1, t2, t3, or t4. Caller maps T1a/T1b to t1. magent does not assign TNM or read slides."
      },
      "fuhrman_grade": {
       "type": "integer",
       "description": "Fuhrman 1982 nuclear grade 1-4 as assigned by the caller (same parsing as Fuhrman). Integer 1-4 only; reject 0, 5, 1.5, and roman I. magent does not read slides."
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/zisman-2002-localized-n0m0-uiss-risk-classifier-rcc-dc9163ee/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)