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FDA Adverse Event Reports (FAERS) Search via 2s.io
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FDA Adverse Event Reports (FAERS) Search via 2s.io is a paid API for AI agents from 2s.io, paid per call via x402, $0.0024/call, status unknown (last checked 2026-09-14).
Search 9M+ FDA adverse drug event reports (since 1968) by drug name and optional MedDRA reaction term, returning report metadata, seriousness flags, patient demographics, and implicated drugs.
Price / call$0.0024
Success—
StatusUnknown
How this service works
Adverse drug event reports from FDA's Adverse Event Reporting System (FAERS) — 9M+ records since 1968 covering serious adverse events, hospitalizations, deaths, and disabilities. Search by drug name (brand/generic/substance, all OR-matched) and optionally filter by MedDRA reaction term. Returns report ID, received date, seriousness flags, patient demographics, MedDRA-coded reactions, implicated drugs (up to 5 per report), and reporting country. Backed by OpenFDA; data is public-domain US government records.
Output
A list of adverse drug event reports from FAERS, each containing report ID, date received, seriousness flags (hospitalization, death, disability, etc.), patient demographics, MedDRA-coded reactions, up to 5 implicated drugs, and the reporting country.
Example use cases
Example prompt
“Pull up the FDA adverse event reports for metformin filtered to 'lactic acidosis' reactions — give me up to 25 reports with seriousness flags and patient details.”
Technical details
Endpoint
GEThttps://2s.io/api/gov/fda-drug-eventsWhen to prefer
Use this endpoint when you need to search real FDA post-market drug safety data for a specific medication, optionally filtered by a specific adverse reaction type. Prefer it over general web searches for authoritative pharmacovigilance data backed by 9M+ government records since 1968.
Side effects
- Drug name not found in FAERS — returns empty results
- MedDRA reaction term misspelled or not a valid preferred term — returns empty or unfiltered results
- Drug name too short (< 2 characters) — returns validation error
- Limit out of range (< 1 or > 100) — returns validation error
- OpenFDA upstream downtime — returns 5xx error
Input
{
"input": {
"type": "http",
"method": "GET",
"queryParams": {
"drug": "aspirin",
"limit": 10
}
}
}Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object |
Output
{
"data": {
"query": {
"drug": "aspirin",
"limit": 10,
"reaction": null
},
"events": [
{
"death": false,
"drugs": [
{
"brandName": "DOXYCYCLINE HYCLATE",
"dosageText": "UNK",
"indication": null,
"medicinalProduct": "DOXYCYCLINE HYCLATE"
},
{
"brandName": "TRAMADOL HYDROCHLORIDE",
"dosageText": "UNK",
"indication": null,
"medicinalProduct": "TRAMADOL HYDROCHLORIDE"
},
{
"brandName": "OXYCONTIN",
"dosageText": "UNK",
"indication": null,
"medicinalProduct": "OXYCONTIN"
},
{
"brandName": null,
"dosageText": "UNK",
"indication": null,
"medicinalProduct": "TALWIN"
},
{
"brandName": null,
"dosageText": "UNK",
"indication": null,
"medicinalProduct": "CODEINE"
}
],
"serious": false,
"disabling": false,
"reactions": [
"Drug hypersensitivity"
],
"patientAge": null,
"patientSex": "Female",
"occurCountry": "US",
"receivedDate": "2014-03-12",
"safetyReportId": "10003304",
"hospitalization": false,
"lifeThreatening": false
},
{
"death": false,
"drugs": [
{
"brandName": "LYRICA",
"dosageText": null,
"indication": null,
"medicinalProduct": "LYRICA"
},
{
"brandName": "METOPROLOL",
"dosageText": null,
"indication": null,
"medicinalProduct": "METOPROLOL"
},
{
"brandName": "XANAX",
"dosageText": null,
"indication": null,
"medicinalProduct": "XANAX"
},
{
"brandName": "LETAIRIS",
"dosageText": "5 MG, UNK",
"indication": "PULMONARY ARTERIAL HYPERTENSION",
"medicinalProduct": "LETAIRIS"
},
{
"brandName": "ADCIRCA",
"dosageText": null,
"indication": null,
"medicinalProduct": "ADCIRCA"
}
],
"serious": false,
"disabling": false,
"reactions": [
"Back pain"
],
"patientAge": "66",
"patientSex": "Female",
"occurCountry": "US",
"receivedDate": "2014-03-12",
"safetyReportId": "10003310",
"hospitalization": false,
"lifeThreatening": false
},
{
"death": false,
"drugs": [
{
"brandName": "AMAZON BASIC CARE ACETAMINOPHEN",
"dosageText": null,
"indication": null,
"medicinalProduct": "ACETAMINOPHEN."
},
{
"brandName": "KESIMPTA",
"dosageText": "300 MG, QD",
"indication": "CHRONIC LYMPHOCYTIC LEUKAEMIA",
"medicinalProduct": "OFATUMUMAB"
},
{
"brandName": null,
"dosageText": null,
"indication": null,
"medicinalProduct": "BAKTAR"
},
{
"brandName": null,
"dosageText": null,
"indication": null,
"medicinalProduct": "ZYLORIC"
},
{
"brandName": null,
"dosageText": null,
"indication": null,
"medicinalProduct": "CHINESE MEDICINE"
}
],
"serious": true,
"disabling": false,
"reactions": [
"Adenoviral haemorrhagic cystitis",
"Pyrexia"
],
"patientAge": "71",
"patientSex": "Male",
"occurCountry": "JP",
"receivedDate": "2014-03-12",
"safetyReportId": "10003321",
"hospitalization": true,
"lifeThreatening": false
},
{
"death": false,
"drugs": [
{
"brandName": null,
"dosageText": "(60 MG X 3),180 MG, DAILY",
"indication": null,
"medicinalProduct": "MORPHINE SULFATE EXTENDED-RELEASE TABLETS (RHODES 74-862)"
},
{
"brandName": null,
"dosageText": "6 X 30 MG, 180 MG DAILY",
"indication": "BACK PAIN",
"medicinalProduct": "MORPHINE SULFATE (SIMILAR TO NDA 19-516)"
},
{
"brandName": "SDAMLO",
"dosageText": "5 MG, UNK",
"indication": "HYPERTENSION",
"medicinalProduct": "AMLODIPINE"
},
{
"brandName": null,
"dosageText": "UNK",
"indication": "HYPERTENSION",
"medicinalProduct": "TRIAMTERENE AND HYDROCHLOROTHIAZID"
},
{
"brandName": "BAYER GENUINE ASPIRIN",
"dosageText": null,
"indication": "PRODUCT USED FOR UNKNOWN INDICATION",
"medicinalProduct": "ASPIRIN"
}
],
"serious": true,
"disabling": false,
"reactions": [
"Cerebrovascular accident",
"Blood pressure increased",
"Pain"
],
"patientAge": null,
"patientSex": "Female",
"occurCountry": "US",
"receivedDate": "2014-03-12",
"safetyReportId": "10003349",
"hospitalization": true,
"lifeThreatening": false
},
{
"death": false,
"drugs": [
{
"brandName": "LETAIRIS",
"dosageText": null,
"indication": "PULMONARY HYPERTENSION",
"medicinalProduct": "LETAIRIS"
},
{
"brandName": "LANTUS",
"dosageText": null,
"indication": null,
"medicinalProduct": "LANTUS"
},
{
"brandName": "LISINOPRIL",
"dosageText": null,
"indication": null,
"medicinalProduct": "LISINOPRIL."
},
{
"brandName": "ALLOPURINOL",
"dosageText": null,
"indication": null,
"medicinalProduct": "ALLOPURINOL."
},
{
"brandName": "KLOR-CON",
"dosageText": null,
"indication": null,
"medicinalProduct": "KLOR-CON"
}
],
"serious": true,
"disabling": false,
"reactions": [
"Oedema peripheral",
"Fluid retention"
],
"patientAge": "84",
"patientSex": "Female",
"occurCountry": "US",
"receivedDate": "2014-03-12",
"safetyReportId": "10003432",
"hospitalization": true,
"lifeThreatening": false
},
{
"death": false,
"drugs": [
{
"brandName": null,
"dosageText": null,
"indication": null,
"medicinalProduct": "LISINOPRIL HCTZ"
},
{
"brandName": "SEROQUEL XR",
"dosageText": null,
"indication": "BIPOLAR I DISORDER",
"medicinalProduct": "SEROQUEL XR"
},
{
"brandName": "SEROQUEL XR",
"dosageText": null,
"indication": "DEPRESSION",
"medicinalProduct": "SEROQUEL XR"
},
{
"brandName": "SEROQUEL XR",
"dosageText": null,
"indication": "BIPOLAR I DISORDER",
"medicinalProduct": "SEROQUEL XR"
},
{
"brandName": "SEROQUEL XR",
"dosageText": null,
"indication": "DEPRESSION",
"medicinalProduct": "SEROQUEL XR"
}
],
"serious": false,
"disabling": false,
"reactions": [
"Hypertension",
"Dehydration",
"Night sweats",
"Panic attack",
"Hyperlipidaemia",
"Insomnia",
"Cold sweat",
"Bipolar disorder",
"Hyperhidrosis",
"Dysgeusia",
"Nausea"
],
"patientAge": "58",
"patientSex": "Male",
"occurCountry": "US",
"receivedDate": "2014-03-12",
"safetyReportId": "10003582",
"hospitalization": false,
"lifeThreatening": false
},
{
"death": false,
"drugs": [
{
"brandName": "JAKAFI",
"dosageText": "15 MG, BID",
"indication": "ESSENTIAL THROMBOCYTHAEMIA",
"medicinalProduct": "JAKAFI"
},
{
"brandName": null,
"dosageText": null,
"indication": null,
"medicinalProduct": "SIMVASTATIN-1A PHARMA"
},
{
"brandName": "DOXAZOSIN",
"dosageText": null,
"indication": null,
"medicinalProduct": "DOXAZOSIN"
},
{
"brandName": "HYDROCHLOROTHIAZIDE",
"dosageText": null,
"indication": null,
"medicinalProduct": "HYDROCHLOROTHIAZIDE"
},
{
"brandName": "ENALAPRIL MALEATE",
"dosageText": null,
"indication": null,
"medicinalProduct": "ENALAPRIL"
}
],
"serious": true,
"disabling": false,
"reactions": [
"Transfusion"
],
"patientAge": null,
"patientSex": "Male",
"occurCountry": "US",
"receivedDate": "2014-03-12",
"safetyReportId": "10003595",
"hospitalization": true,
"lifeThreatening": false
},
{
"death": false,
"drugs": [
{
"brandName": "REVLIMID",
"dosageText": "15 MILLIGRAM",
"indication": "PLASMA CELL MYELOMA",
"medicinalProduct": "REVLIMID"
},
{
"brandName": "REVLIMID",
"dosageText": "10 MILLIGRAM",
"indication": null,
"medicinalProduct": "REVLIMID"
},
{
"brandName": "PLAVIX",
"dosageText": null,
"indication": "PRODUCT USED FOR UNKNOWN INDICATION",
"medicinalProduct": "PLAVIX"
},
{
"brandName": "PLAVIX",
"dosageText": "75 MILLIGRAM",
"indication": null,
"medicinalProduct": "PLAVIX"
},
{
"brandName": null,
"dosageText": null,
"indication": "PRODUCT USED FOR UNKNOWN INDICATION",
"medicinalProduct": "FISH OIL - VITAMIN D3"
}
],
"serious": true,
"disabling": false,
"reactions": [
"Influenza",
"Pneumonia"
],
"patientAge": "77",
"patientSex": "Male",
"occurCountry": "US",
"receivedDate": "2014-03-12",
"safetyReportId": "10003632",
"hospitalization": true,
"lifeThreatening": true
},
{
"death": false,
"drugs": [
{
"brandName": "DIOVAN",
"dosageText": "40 MG, BID",
"indication": null,
"medicinalProduct": "DIOVAN"
},
{
"brandName": null,
"dosageText": "120 UG, QD",
"indication": null,
"medicinalProduct": "DILTIAZEM"
},
{
"brandName": "ECOTRIN",
"dosageText": "81 MG, UNK",
"indication": null,
"medicinalProduct": "ECOTRIN"
},
{
"brandName": null,
"dosageText": null,
"indication": null,
"medicinalProduct": "ATORVASTATIN"
},
{
"brandName": "LIPITOR",
"dosageText": "20 MG, QD",
"indication": null,
"medicinalProduct": "LIPITOR"
}
],
"serious": true,
"disabling": true,
"reactions": [
"Chronic obstructive pulmonary disease",
"Emphysema",
"Bronchitis",
"Dyspnoea",
"Stress",
"Anxiety"
],
"patientAge": null,
"patientSex": "Male",
"occurCountry": "US",
"receivedDate": "2014-03-12",
"safetyReportId": "10003701",
"hospitalization": true,
"lifeThreatening": false
},
{
"death": false,
"drugs": [
{
"brandName": "JAKAFI",
"dosageText": "5 MG, BID",
"indication": null,
"medicinalProduct": "JAKAFI"
},
{
"brandName": "JAKAFI",
"dosageText": "5 MG, QD",
"indication": null,
"medicinalProduct": "JAKAFI"
},
{
"brandName": null,
"dosageText": null,
"indication": null,
"medicinalProduct": "ATORVASTATIN"
},
{
"brandName": null,
"dosageText": null,
"indication": null,
"medicinalProduct": "APEXICON"
},
{
"brandName": null,
"dosageText": null,
"indication": null,
"medicinalProduct": "MENEST /00073001/"
}
],
"serious": false,
"disabling": false,
"reactions": [
"Rash",
"Dyspnoea"
],
"patientAge": null,
"patientSex": "Female",
"occurCountry": "US",
"receivedDate": "2014-03-12",
"safetyReportId": "10003713",
"hospitalization": false,
"lifeThreatening": false
}
],
"source": {
"url": "https://open.fda.gov/apis/drug/event/",
"license": "Public domain (US government records)",
"provider": "OpenFDA — Drug Adverse Event Reports (FAERS)"
},
"returned": 10,
"totalCount": 771408
},
"meta": {
"cost": {
"usd": 0.0024,
"tier": 0
},
"caller": "x402",
"version": null,
"endpoint": "gov.fda-drug-events",
"settlement": {
"txHash": "0xb4215b2e3fa5844fa6419feb19ce017d962d06021745f31ce451b6b022c3c36f",
"network": "eip155:8453",
"success": true
}
}
}Tags
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