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4Ts Score Calculator for Heparin-Induced Thrombocytopenia (HIT)
x402
4Ts Score Calculator for Heparin-Induced Thrombocytopenia (HIT) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Computes the Lo 2006 4Ts pretest probability score for heparin-induced thrombocytopenia (HIT), returning a sum (0–8) and risk band (low/intermediate/high).
Price / call$0.005
Success—
StatusUnknown
How this service works
4Ts score (Lo 2006) for heparin-induced thrombocytopenia pretest probability. Four caller-assigned integers 0-2 (thrombocytopenia, timing, thrombosis, other causes) using the published table; magent sums only (max 8). Bands 0-3 low, 4-5 intermediate, and 6-8 high pretest probability. Not a diagnosis of HIT, not the HEP score, and not an antibody result. magent does not grade platelet counts or day of onset.
Output
Returns the integer sum of the four caller-assigned 4Ts components (range 0–8) and a risk classification band: 0–3 = low pretest probability, 4–5 = intermediate, 6–8 = high. Does not return a diagnosis, antibody result, or HEP score.
Example use cases
HIT workup triage in the ICU
“My ICU patient developed a 55% platelet drop on day 6 of heparin and has a new DVT — I'm assigning 2 for thrombocytopenia, 2 for timing, 2 for thrombosis, and 2 for other causes (no obvious alternative). Calculate the 4Ts score and tell me the risk band.”
Low-risk reassurance before continuing heparin
“My patient's platelet fell 20% on day 2 of heparin with no thrombosis and a clear alternative cause. I'm scoring 0 for thrombocytopenia, 0 for timing, 0 for thrombosis, and 0 for other causes — run the 4Ts calculation and confirm whether this is low probability for HIT.”
Intermediate probability guiding antibody testing decision
“I have a patient with a 35% platelet decline, timing consistent with days 5–10 but not clear, erythematous skin lesions at the heparin site, and a possible alternative cause — that's 1 for thrombocytopenia, 1 for timing, 1 for thrombosis, and 1 for other causes. What's the 4Ts total and pretest probability band?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/four_tsWhen to prefer
Use this endpoint when you need a fast, deterministic Lo 2006 4Ts score sum and risk band without building the arithmetic yourself. Prefer it over a generic LLM calculation when you need reproducible, auditable clinical scoring. It is not the HEP score and not an antibody assay interpreter — use a different tool for those. Best suited for clinical decision support pipelines where the calling agent or clinician has already assigned the four Lo 2006 point values.
Side effects
- Any of the four integer parameters (thrombocytopenia, timing, thrombosis, other_causes) missing → validation error
- Values outside the 0–2 integer range for any parameter → likely rejection or unexpected behavior
- Non-integer (float or string) inputs for score fields → schema validation failure
- Caller incorrectly pre-grades platelet counts or timing — magent does not sanity-check clinical assignments, so miscoded inputs yield a valid but clinically wrong score
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"path": "/api/calc/four_ts",
"count": 2,
"items": [
{
"score": 0,
"formula": "four_ts",
"citation": {
"id": "lo-2006",
"doi": "10.1111/j.1538-7836.2006.01787.x",
"title": "Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings",
"source": "J Thromb Haemost. 2006;4(4):759-765",
"authors": "Lo GK, Juhl D, Warkentin TE, Sigouin CS, Eichler P, Greinacher A"
},
"max_score": 8,
"components": [
{
"value": 0,
"factor": "thrombocytopenia",
"points": 0,
"present": false
},
{
"value": 0,
"factor": "timing",
"points": 0,
"present": false
},
{
"value": 0,
"factor": "thrombosis",
"points": 0,
"present": false
},
{
"value": 0,
"factor": "other_causes",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"four_ts_band": "0-3",
"formula_expression": "4Ts = thrombocytopenia + timing + thrombosis + other_causes; each 0-2 caller-assigned from Lo 2006 table; pretest probability low 0-3, intermediate 4-5, high 6-8; max 8"
},
{
"score": 0,
"formula": "four_ts",
"citation": {
"id": "lo-2006",
"doi": "10.1111/j.1538-7836.2006.01787.x",
"title": "Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings",
"source": "J Thromb Haemost. 2006;4(4):759-765",
"authors": "Lo GK, Juhl D, Warkentin TE, Sigouin CS, Eichler P, Greinacher A"
},
"max_score": 8,
"components": [
{
"value": 0,
"factor": "thrombocytopenia",
"points": 0,
"present": false
},
{
"value": 0,
"factor": "timing",
"points": 0,
"present": false
},
{
"value": 0,
"factor": "thrombosis",
"points": 0,
"present": false
},
{
"value": 0,
"factor": "other_causes",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"four_ts_band": "0-3",
"formula_expression": "4Ts = thrombocytopenia + timing + thrombosis + other_causes; each 0-2 caller-assigned from Lo 2006 table; pretest probability low 0-3, intermediate 4-5, high 6-8; max 8"
}
]
}
}Tags
x402
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