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Absolute Lymphocyte Count (ALC) Calculator — Shapiro 1998
x402
Absolute Lymphocyte Count (ALC) Calculator — Shapiro 1998 is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).
Calculates absolute lymphocyte count from WBC and lymphocyte percentage, and predicts CD4 count category using the Shapiro 1998 rule (ALC <1000 → CD4 <200; ALC ≥2000 → CD4 ≥200).
Price / call$0.005
Success—
StatusUnknown
How this service works
Absolute lymphocyte count from WBC and lymphocyte percent (Shapiro 1998). ALC < 1000 cells/mm3 predicts CD4 < 200; ALC >= 2000 predicts CD4 >= 200. Deterministic published arithmetic with citation. Not a CD4 measurement or HIV diagnosis. magent does not measure the CBC.
Output
Returns the computed absolute lymphocyte count (ALC) in cells/mm³, along with the Shapiro 1998 CD4 prediction category (CD4 <200, indeterminate, or CD4 ≥200) based on ALC thresholds of 1000 and 2000 cells/mm³.
Example use cases
CD4 surrogate estimate in resource-limited setting
“I have a patient with WBC 3.2 k/µL and lymphocytes at 18%. Use the Shapiro 1998 ALC rule to figure out whether their CD4 is likely below or above 200.”
HIV monitoring without CD4 test
“Our clinic doesn't have CD4 testing available — can you calculate the ALC from a WBC of 5800 cells/µL and 22% lymphocytes and tell me if the Shapiro rule predicts CD4 deficiency?”
Automated CBC result enrichment
“For a patient whose CBC shows WBC 7.1 k/uL and 35% lymphocytes, compute the ALC and apply the Shapiro 1998 formula to predict their CD4 count category.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/alcWhen to prefer
Use this endpoint when you need a fast, deterministic ALC calculation and CD4 category prediction based on the peer-reviewed Shapiro 1998 formula, especially in workflows processing CBC results where CD4 testing is unavailable. Prefer it over manual arithmetic or general-purpose calculators when you need a citable, published clinical decision rule with clear ALC thresholds.
Side effects
- Missing required lymphocyte_percent parameter returns a validation error
- WBC value out of range (e.g. wbc_ul not between 10–500000) may return an error or unexpected result
- Neither wbc_ul nor wbc_k_ul provided results in a missing-parameter error
- lymphocyte_percent out of range (0.1–99) may cause a validation error
- x402 payment failure if insufficient USDC balance prevents the call from completing
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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