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Age-Adjusted D-dimer Cutoff Calculator (Righini 2014 ADJUST-PE)
x402
Age-Adjusted D-dimer Cutoff Calculator (Righini 2014 ADJUST-PE) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Calculates whether PE can be excluded based on the Righini 2014 ADJUST-PE age-adjusted D-dimer cutoff: below 500 ng/mL FEU if age <50, or below age×10 ng/mL FEU if age ≥50.
Price / call$0.005
Success—
StatusUnknown
How this service works
Age-adjusted D-dimer cutoff (Righini 2014 ADJUST-PE). PE excluded only when D-dimer (ng/mL FEU) is strictly below 500 if age <50 or age×10 if age ≥50. Equality is not excluded. FEU only, not DDU; magent does not convert units. Not a diagnosis, not YEARS, not Wells.
Output
Returns the age-adjusted D-dimer cutoff in ng/mL FEU for the given patient age, whether the provided D-dimer value is strictly below the cutoff (PE excluded), and the rule applied (500 ng/mL if age <50, age×10 if age ≥50). Equality with the cutoff is NOT considered exclusion.
Example use cases
ED PE workup for elderly patient
“I have a 74-year-old patient with a D-dimer of 710 ng/mL FEU. Using the age-adjusted D-dimer cutoff from the ADJUST-PE study, does this value exclude pulmonary embolism?”
Younger patient with borderline D-dimer
“My 43-year-old patient has a D-dimer of 490 ng/mL FEU in FEU units — can I use the Righini 2014 criteria to rule out PE with that result?”
Automated clinical decision pipeline
“For a 58-year-old patient, calculate whether a D-dimer of 575 ng/mL FEU falls below the age-adjusted ADJUST-PE cutoff and tell me if PE is excluded.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/age_adjusted_dimerWhen to prefer
Use this endpoint when you need to apply the Righini 2014 ADJUST-PE age-adjusted D-dimer cutoff specifically — i.e., the rule that raises the threshold to age×10 ng/mL FEU for patients aged 50 and above. Prefer this over generic D-dimer lookups when the clinical context is PE rule-out in a low-to-intermediate pretest probability patient and D-dimer values are already in FEU (ng/mL). Do not use for YEARS criteria, Wells score, DDU units, or any diagnostic purpose beyond supporting the ADJUST-PE decision rule.
Side effects
- Age outside 18–120 integer range returns a validation error
- D-dimer value outside 0–20000 range returns a validation error
- D-dimer provided in DDU instead of FEU will produce clinically incorrect results (no unit conversion is performed)
- Missing required query parameters (age or d_dimer_ng_ml) returns a 400-level error
- Non-integer age value will fail schema validation
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"path": "/api/calc/age_adjusted_dimer",
"count": 2,
"items": [
{
"formula": "age_adjusted_dimer",
"citation": {
"id": "righini-2014",
"doi": "10.1001/jama.2014.2135",
"title": "Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study",
"source": "JAMA. 2014;311(11):1117-1124",
"authors": "Righini M, Van Es J, Den Exter PL, et al."
},
"criteria": [
{
"met": false,
"value": 40,
"factor": "age_ge_50"
}
],
"age_years": 40,
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"pe_excluded": true,
"d_dimer_ng_ml": 499,
"ctpa_indicated": false,
"formula_expression": "PE excluded iff d_dimer_ng_ml < (500 if age < 50 else age * 10); D-dimer is ng/mL FEU; equality is not excluded",
"d_dimer_threshold_ng_ml": 500
},
{
"formula": "age_adjusted_dimer",
"citation": {
"id": "righini-2014",
"doi": "10.1001/jama.2014.2135",
"title": "Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study",
"source": "JAMA. 2014;311(11):1117-1124",
"authors": "Righini M, Van Es J, Den Exter PL, et al."
},
"criteria": [
{
"met": false,
"value": 40,
"factor": "age_ge_50"
}
],
"age_years": 40,
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"pe_excluded": true,
"d_dimer_ng_ml": 499,
"ctpa_indicated": false,
"formula_expression": "PE excluded iff d_dimer_ng_ml < (500 if age < 50 else age * 10); D-dimer is ng/mL FEU; equality is not excluded",
"d_dimer_threshold_ng_ml": 500
}
]
}
}Tags
x402
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