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APRI Calculator (AST-to-Platelet Ratio Index)
x402
APRI Calculator (AST-to-Platelet Ratio Index) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Calculates the Wai 2003 AST-to-Platelet Ratio Index (APRI) from AST, lab-specific AST ULN, and platelet count, returning the score plus published cut-offs for significant fibrosis and cirrhosis.
Price / call$0.005
Success—
StatusUnknown
How this service works
Wai 2003 AST to platelet ratio index (APRI) from AST, laboratory AST ULN, and platelet count. Returns APRI to two decimals plus published training-set cut-offs for significant fibrosis (Ishak ≥3) and cirrhosis. ULN is required; magent does not assume 40 U/L. Not a diagnosis, not FIB-4, and not a biopsy.
Output
Returns the APRI score rounded to two decimal places, along with the Wai 2003 published training-set cut-offs for significant fibrosis (Ishak ≥3) and cirrhosis, and an indication of whether the patient's score meets or exceeds those thresholds. Does not return a clinical diagnosis.
Example use cases
Hepatitis C fibrosis staging support
“My hepatitis C patient has an AST of 95 U/L, the lab ULN here is 40 U/L, and platelets are 130 × 10⁹/L. What's their APRI score and does it suggest significant fibrosis or cirrhosis?”
Non-alcoholic fatty liver disease monitoring
“I'm tracking a NAFLD patient over time — today's AST is 58 U/L, our institution's ULN is 35 U/L, and platelets are 210 × 10⁹/L. Compute the APRI so I can compare it to last quarter's result.”
Pre-treatment cirrhosis risk triage
“Before starting antiviral therapy, I need a quick APRI on this patient: AST 140 U/L, the lab's ULN is 45 U/L, platelets 88 × 10⁹/L. Flag if it hits the cirrhosis threshold.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/apriWhen to prefer
Use this endpoint when you need a fast, formula-based APRI calculation that correctly uses the caller-supplied lab ULN rather than assuming 40 U/L — critical when integrating with labs that use non-standard reference ranges. Prefer this over FIB-4 when platelet count and AST are available but patient age is not, or when the clinical question is specifically framed around the Wai 2003 APRI cut-offs rather than FIB-4 thresholds.
Side effects
- Missing required parameter (ast_u_l, ast_uln_u_l, or platelets_10e9_l) returns a 400-level error
- Values outside accepted ranges (e.g. platelets <1 or >2000, AST ULN <5 or >200) may be rejected or return a validation error
- Payment failure (x402) if USDC balance is insufficient
- Network timeout on slow connections
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"path": "/api/calc/apri",
"count": 2,
"items": [
{
"apri": 1.67,
"ast_u_l": 90,
"formula": "apri",
"citation": {
"id": "wai-2003",
"doi": "10.1053/jhep.2003.50346",
"title": "A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C",
"source": "Hepatology. 2003;38(2):518-526",
"authors": "Wai CT, Greenson JK, Fontana RJ, et al."
},
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"ast_uln_u_l": 45,
"platelets_10e9_l": 120,
"wai_fibrosis_band": "high",
"formula_expression": "APRI = ((AST / AST_ULN) / platelet_count_10e9_L) * 100",
"wai_cirrhosis_band": "indeterminate"
},
{
"apri": 1.67,
"ast_u_l": 90,
"formula": "apri",
"citation": {
"id": "wai-2003",
"doi": "10.1053/jhep.2003.50346",
"title": "A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C",
"source": "Hepatology. 2003;38(2):518-526",
"authors": "Wai CT, Greenson JK, Fontana RJ, et al."
},
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"ast_uln_u_l": 45,
"platelets_10e9_l": 120,
"wai_fibrosis_band": "high",
"formula_expression": "APRI = ((AST / AST_ULN) / platelet_count_10e9_L) * 100",
"wai_cirrhosis_band": "indeterminate"
}
]
}
}Tags
x402
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