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ASTCT ICANS Consensus Grade Calculator (Adult, Lee 2019)
x402
ASTCT ICANS Consensus Grade Calculator (Adult, Lee 2019) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-13).
Computes the adult ASTCT ICANS consensus grade (0–4) from five caller-supplied domain scores: ICE score, level of consciousness, seizure, motor weakness, and ICP/edema.
Price / call$0.005
Success—
StatusUnknown
How this service works
Adult ASTCT ICANS consensus grade (Lee 2019 Table 6). Grade is the most severe of ICE, depressed LOC, seizure, deep focal motor weakness, and ICP/edema. ICE 10 is 0; 7-9 is 1; 3-6 is 2; 0-2 is 3; ICE 0 is 4 if unarousable. Not CRS, not pediatric CAPD, and not the 10-item ICE test. magent does not perform ICE testing or examine the patient. Not a medical device.
Output
Returns the overall ICANS grade (0–4) as the maximum severity across the five domains (ICE, depressed LOC, seizure, deep focal motor weakness, ICP/edema), along with per-domain grade values, consistent with Lee 2019 Table 6 criteria.
Example use cases
CAR-T neurotoxicity triage
“My patient just received CAR-T therapy and has an ICE score of 3, only wakes up to tactile stimulation, no seizures, no focal motor weakness, and diffuse cerebral edema on imaging — what is the ICANS grade?”
Clinical trial automated ICANS scoring
“For our CAR-T trial data pipeline, calculate the ASTCT ICANS grade for a participant with ICE score 9, spontaneous awakening, no seizure, no motor weakness, and no ICP findings.”
Complete neurotoxicity assessment at grade boundary
“Can you work out the ICANS grade for a patient with ICE score 0, unarousable level of consciousness, a rapidly resolving seizure, no focal motor weakness, and focal edema on neuroimaging?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/astct_icansWhen to prefer
Use this endpoint when you need a fast, deterministic computation of the adult ASTCT ICANS consensus grade per Lee 2019 Table 6, particularly in CAR-T care workflows, clinical trial pipelines, or agentic monitoring systems. Prefer this over manual look-up tables or generic LLM reasoning when you require reproducible, schema-validated grading that can be audited. Not appropriate for pediatric CAPD grading, CRS scoring, or situations where ICE testing has not already been performed by a clinician.
Side effects
- Missing required query parameter (ice_score, loc, seizure, motor_weakness, or icp) returns a 400/422 error
- ice_score out of range (not 0–10) returns a validation error
- Invalid enum value for loc, seizure, motor_weakness, or icp returns an error
- Network or server errors return 5xx; retry with backoff
- Payment failure (x402) if USDC balance is insufficient
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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