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Barbour 2019 IgAN 5-Year Risk Model (Race-Free)
x402
Barbour 2019 IgAN 5-Year Risk Model (Race-Free) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Calculates the 5-year risk of 50% eGFR decline or ESKD in IgA nephropathy patients using the Barbour 2019 race-free Cox model with age, eGFR, MAP, proteinuria, Oxford MEST scores, and treatment variables.
Price / call$0.005
Success—
StatusUnknown
How this service works
Barbour 2019 race-free full IgAN model: 5-year risk of 50% eGFR decline or ESKD from age, eGFR, MAP, proteinuria g/day, Oxford MEST, RAS blockade, and immunosuppression at biopsy. Risk = 1 - S0(60)^exp(LP) with eTable 3 coefficients. Caller supplies eGFR; magent does not compute CKD-EPI or score the biopsy. Not the race/ethnicity model. Not KFRE. Not a diagnosis or treatment order. Not a medical device.
Output
Returns the computed 5-year risk (probability) of 50% eGFR decline or end-stage kidney disease, derived from the Barbour 2019 race-free Cox proportional hazards model. Output includes the linear predictor (LP) and the final risk estimate: 1 − S0(60)^exp(LP), using the published eTable 3 coefficients. Does not return a diagnosis, treatment recommendation, or biopsy scoring.
Example use cases
Pre-visit IgAN risk stratification
“My nephrologist wants a 5-year ESKD risk estimate before the clinic visit. The patient is 35 years old, eGFR 68, MAP 95 mmHg, proteinuria 0.6 g/day, biopsy MEST is M0, E1, S0, T0, they're on an ACE inhibitor but not on immunosuppression. Can you run the Barbour 2019 race-free IgAN model?”
Comparing risk before and after treatment
“I want to see how much the Barbour 2019 IgAN risk score changes if we consider the patient as being on RAS blockade versus not. Patient is 50 years old, eGFR 45, MAP 110, proteinuria 2.5 g/day, MEST M1 E0 S1 T2, no immunosuppression. First run with RAS blockade true, then with false.”
High-risk IgAN workup documentation
“Help me document the predicted 5-year risk for a 29-year-old IgAN patient with eGFR 38, MAP 118, proteinuria 3.2 g/day, Oxford MEST M1 E1 S1 T2, not on RAS blockade, currently on immunosuppression. Use the Barbour 2019 race-free model.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/igan_predictWhen to prefer
Use this endpoint when you need the Barbour 2019 race-free Cox model specifically for IgA nephropathy prognosis and have pre-scored Oxford MEST pathology values and a caller-supplied eGFR. Prefer this over KFRE (which is not IgAN-specific and does not use MEST scores) or the Barbour race/ethnicity model variant. Do not use for CKD of other etiologies, diagnosis, or treatment planning.
Side effects
- Missing required query parameters (age, eGFR, MAP, proteinuria, all four MEST scores, rasb_at_biopsy, immunosuppression_at_biopsy) return a validation error
- Out-of-range values (e.g., age < 18, proteinuria > 20, MAP outside 30–180) may trigger rejection or undefined behavior
- mest_t values other than 0, 1, or 2 are invalid and will be rejected
- mest_m/e/s values other than 0 or 1 are invalid
- Boolean fields rasb_at_biopsy or immunosuppression_at_biopsy sent as strings instead of true/false may fail parsing
- Network or payment (x402) errors may prevent the call from completing
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
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