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CARG Toxicity Score Calculator (Hurria 2011)
x402
CARG Toxicity Score Calculator (Hurria 2011) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Computes the Cancer and Aging Research Group (CARG) chemotherapy toxicity score from 11 caller-supplied clinical flags and returns risk category (low/intermediate/high) with predicted grade 3–5 toxicity probability.
Price / call$0.005
Success—
StatusUnknown
How this service works
Hurria 2011 Table 5 CARG toxicity: age ≥72 (+2), GI/GU (+2, not inverted), standard dose (+2), polychemotherapy (+2), Hb male <11 or female <10 g/dL (+3), caller-assigned Jelliffe CrCl <34 (+3; magent does not compute Jelliffe), hearing fair/worse (+2), ≥1 fall in 6 months (+3), limited walking 1 block (+2), help with meds (+1), decreased social activity (+1). Max 19. 0-5 low 30%, 6-9 intermediate 52%, 10-19 high 83%. Not the 2016 revision, not CRASH, not a chemo order.
Output
Returns the integer CARG total score (0–19), the risk tier (low 0–5, intermediate 6–9, or high 10–19), and the associated predicted grade 3–5 chemotherapy toxicity probability (approximately 30%, 52%, or 83% respectively), based on the Hurria 2011 Table 5 derivation cohort.
Example use cases
Pre-chemo toxicity screening in clinic
“Before we start this 78-year-old female patient on standard-dose polychemotherapy for colorectal cancer, can you run her CARG score? Her hemoglobin is 9.2 g/dL, Jelliffe CrCl is 30 mL/min, she had two falls in the past 6 months, her hearing is poor, she needs help with medications, her social activity has decreased, and she can't walk a full block.”
Low-risk patient chemo clearance
“I want to confirm this 68-year-old male lung cancer patient is low risk before starting chemo. Hemoglobin 13.5 g/dL, Jelliffe CrCl 60 mL/min, no falls, normal hearing, independent with meds, socially active, can walk a block — it's standard-dose single-agent, not polychemotherapy.”
Documenting toxicity risk tier in oncology note
“For the oncology note, what CARG risk category is a 73-year-old female with GU cancer, hemoglobin 10.5 g/dL, CrCl 40 mL/min, no falls, hearing is good, dose-reduced chemotherapy (not standard), no polychemotherapy, needs help with meds, and decreased social activity but walks fine?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/carg_ttWhen to prefer
Use this endpoint when you need the original Hurria 2011 CARG Table 5 integer score for geriatric oncology patients being considered for chemotherapy. Prefer it over general risk calculators when the clinical workflow requires an explicit toxicity risk tier (low/intermediate/high) with the published toxicity probabilities. Note that this is not the 2016 revised CARG, not CRASH, and does not generate chemotherapy orders or compute Jelliffe CrCl — those inputs must be supplied by the caller.
Side effects
- Missing required query parameter returns 400 error — all 12 fields are mandatory
- Out-of-range hemoglobin (outside 3–22 g/dL) or age (outside 18–120) rejected
- Invalid enum value for sex (must be 'male' or 'female') causes validation error
- Caller must supply Jelliffe CrCl — magent does not compute it from creatinine/demographics
- Boolean fields passed as strings instead of true/false may cause parse errors
- This endpoint implements 2011 Hurria, not the 2016 revision — results will differ from tools using updated weights
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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