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Chemical Compatibility Checker
x402
Chemical Compatibility Checker is a paid API for AI agents from toolcall.click, paid per call via x402, $0.03/call, status unknown (last checked 2026-09-14).
Checks whether two chemicals can be safely mixed or stored together, returning a safety verdict, hazard reasons, and expected effects based on PubChem GHS data and CAMEO reactivity profiles
Price / call$0.03
Success—
StatusUnknown
How this service works
Can chemical A be safely mixed or stored with chemical B? Pass two CAS numbers or names. Returns a verdict (incompatible / caution / no_known_hazard), the reason, expected effects (gas evolution, heat, fire, toxic fumes) and confidence, from expert reasoning over PubChem GHS data and CAMEO-derived reactivity profiles. JSON response. $0.03 USDC per call, pay via x402, no API key.
Output
A JSON object containing a compatibility verdict (incompatible, caution, or no_known_hazard), a plain-language reason explaining the hazard or lack thereof, a list of expected physical/chemical effects such as gas evolution, heat generation, fire risk, or toxic fume production, and a confidence score reflecting certainty of the assessment.
Example use cases
Lab storage safety screening
“I need to check if it's safe to store sulfuric acid and sodium hydroxide in the same cabinet. Can you tell me if they're incompatible, why, and what could happen if they accidentally come into contact?”
Hazmat incident pre-screening
“We had a spill involving bleach and ammonia in our facility. Can you check if these two chemicals are dangerous to mix, what the hazard reason is, and what effects the people nearby might have been exposed to?”
Industrial solvent compatibility check
“Before we combine methanol and chloroform in our process line, can you verify whether these two solvents are safe to mix together, flag any incompatibilities, and tell me what physical or chemical effects I should watch out for?”
Technical details
Endpoint
GEThttps://toolcall.click/t/chem/compatibilityWhen to prefer
Choose this endpoint when you need a quick, structured chemical compatibility assessment for any two substances identified by name or CAS number, especially in lab safety workflows, chemical storage planning, hazmat screening, or industrial process checks. It is preferable over manual literature lookup when you need machine-readable verdicts with confidence scores derived from authoritative PubChem GHS and CAMEO data.
Side effects
- Unrecognized chemical name or CAS number returns an error or low-confidence result
- Obscure or novel chemicals may have insufficient GHS/CAMEO data, yielding low confidence
- Missing required query parameters (a or b) returns a 400 or validation error
- Payment failure via x402 results in a 402 Payment Required response
- Network timeout or service unavailability returns a 503 error
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"a": {
"name": "Sodium Hypochlorite"
},
"b": {
"name": "Ammonia"
},
"reason": "Forms toxic chloramine gases",
"verdict": "incompatible",
"confidence": 0.95,
"expectedEffects": [
"toxic fumes"
]
}
}Tags
x402
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