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ClinicalTrials.gov Trial Search
x402
ClinicalTrials.gov Trial Search is a paid API for AI agents from payai.agentstools.dev, paid per call via x402, $0.015/call, status unknown (last checked 2026-09-14).
Search ClinicalTrials.gov by indication, molecule, sponsor, or free text and return a ranked, normalized list of matching clinical trial records with facet summary and total count.
Price / call$0.015
Success—
StatusUnknown
How this service works
Search ClinicalTrials.gov by indication, company, molecule or free text and get a ranked list of normalized trial records with total count and on-page facet summary. Optional phase, status, study-type and country filters. A cheap first step before /trials/study or /trials/pipeline.
Output
A ranked list of normalized clinical trial records (up to page_size, default 10), each containing core metadata such as NCT identifier, official title, overall status, phase, sponsor, conditions, interventions, and locations. Also includes a total matching-record count and an on-page facet summary (e.g. phase distribution, status breakdown) to help the agent decide whether to refine the query or drill into individual study records.
Example use cases
Competitor pipeline intelligence
“Search for all Phase 2 and Phase 3 trials where Pfizer is the lead sponsor testing any oncology drug — give me up to 20 results so I can map out their pipeline.”
Patient recruitment opportunity scan
“Find recruiting interventional trials for Crohn's disease in Germany right now — I need the first 15 results to identify sites we might partner with for patient recruitment.”
Molecule competitive landscape check
“Look up clinical trials on ClinicalTrials.gov for semaglutide across all phases and statuses, return up to 25 results so I can see the full competitive landscape before our strategy meeting.”
Technical details
Endpoint
GEThttps://payai.agentstools.dev/trials/searchWhen to prefer
Use this endpoint as the first step in any clinical-trial research workflow when you need to discover and shortlist relevant trials from ClinicalTrials.gov. It is the right choice when you have a condition, molecule, or sponsor name and want a broad ranked list before investing in detailed per-study lookups (e.g. /trials/study) or pipeline analyses (e.g. /trials/pipeline). Prefer this over manual ClinicalTrials.gov browsing when you need structured, normalized, filterable output programmatically. It is a low-cost ($0.015) way to validate whether a topic has any trial coverage before running more expensive downstream queries.
Side effects
- No results returned if query terms are too specific or misspelled — agent should broaden or correct input
- Missing required 'input' wrapper causes 400 validation error
- Phase enum must be '0','1','2','3', or '4' — numeric strings only, not 'Phase 2'
- Status enum uses snake_case values (e.g. 'not_yet_recruiting') — freeform text will be rejected
- page_size must be between 1 and 50 — values outside range cause validation failure
- Country must match ClinicalTrials.gov accepted country names; ambiguous abbreviations may return zero results
- Service may return stale data if ClinicalTrials.gov upstream is delayed
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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