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CLL-IPI 2016 Calculator
x402
CLL-IPI 2016 Calculator is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-13).
Computes the CLL-IPI 2016 prognostic score for chronic lymphocytic leukaemia, categorizing risk as low, intermediate, high, or very high based on five clinical parameters.
Price / call$0.005
Success—
StatusUnknown
How this service works
CLL-IPI 2016 for chronic lymphocytic leukaemia: TP53 abnormality (del(17p) and/or TP53 mutation) 4, unmutated IGHV 2, beta-2 microglobulin >3.5 mg/L 2, advanced stage (Binet B/C or Rai I–IV) 1, age >65 1; max 10. Low 0–1, intermediate 2–3, high 4–6, very_high 7–10. Deterministic published score with citation; not a CLL diagnosis; not Shipp IPI; not MIPI. magent does not assay TP53, IGHV, or beta-2 microglobulin.
Output
Returns the numeric CLL-IPI total score (0–10) and a categorical risk label — low (0–1), intermediate (2–3), high (4–6), or very_high (7–10) — based on the 2016 published algorithm and component point contributions.
Example use cases
Prognosis stratification at CLL diagnosis
“My patient is 72 years old, has a confirmed TP53 mutation, unmutated IGHV, beta-2 microglobulin of 5.1 mg/L, and is Rai stage II — can you run the CLL-IPI 2016 and tell me their risk group?”
Clinical trial eligibility risk screening
“For a 60-year-old CLL patient with no TP53 abnormality, mutated IGHV, beta-2 microglobulin of 2.8 mg/L, and Binet A stage, what does the CLL-IPI 2016 score come out to?”
Longitudinal risk re-assessment after restaging
“After restaging, my 67-year-old CLL patient now has advanced disease (Binet C), TP53 deletion detected, IGHV unmutated, and beta-2 microglobulin of 3.9 mg/L — recalculate their CLL-IPI score and risk category.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/cll_ipiWhen to prefer
Use this endpoint when you need a deterministic, citation-backed CLL-IPI 2016 score computation and already have the five required clinical values (TP53 status, IGHV mutation status, beta-2 microglobulin level, clinical stage, patient age) pre-assayed. Prefer this over building your own scoring logic to ensure alignment with the published 2016 algorithm. This is not a diagnostic tool for CLL, does not perform any laboratory assays, and is not appropriate for Shipp IPI, MIPI, or other lymphoma prognostic indices.
Side effects
- Missing required parameters (tp53_abnormal, ighv_unmutated, beta2_microglobulin_mg_l, advanced_stage, age) returns a validation error
- beta2_microglobulin_mg_l outside range 0.2–40 may be rejected or flagged
- age outside range 18–120 returns a validation error
- Payment failure (insufficient USDC balance or missing x402 header) blocks the request
- Caller supplying biologically inconsistent inputs (e.g. negative beta-2 microglobulin) will receive an error
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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