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Dutch Lipid Clinic Network (DLCN) Familial Hypercholesterolaemia Score
x402
Dutch Lipid Clinic Network (DLCN) Familial Hypercholesterolaemia Score is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).
Calculates the Dutch Lipid Clinic Network (Nordestgaard 2013 Table 1) FH score from LDL cholesterol, family history, clinical history, physical findings, and DNA mutation status.
Price / call$0.005
Success—
StatusUnknown
How this service works
Dutch Lipid Clinic Network (Nordestgaard 2013 Table 1) familial hypercholesterolaemia score. One LDL (mmol/L or mg/dL / 38.67) plus family, clinical, physical, and DNA groups; per group only the highest. Max 26. Definite >8, probable 6-8, possible 3-5, unlikely 0-2. Score 8 (mutation alone) is probable. Adult Table 1 only; not Simon Broome, not MEDPED, not homozygous FH. magent does not assay lipids, examine tendons or arcus, or sequence genes. Not a medical device and not a diagnosis of FH.
Output
Returns the total DLCN FH score (0–26) broken down by group (lipid, family, clinical, physical, DNA), with per-group highest-item selection applied, plus a categorical FH probability label: definite (>8), probable (6–8), possible (3–5), or unlikely (0–2).
Example use cases
Lipid clinic FH triage
“I have a patient with LDL of 6.9 mmol/L, a father who had a heart attack at age 48, no tendon xanthomas, no corneal arcus, no children with high LDL, and no genetic test results yet — what is their Dutch FH score and how likely is familial hypercholesterolaemia?”
Post-genetic-test FH classification
“A patient just got back a confirmed LDLR pathogenic variant. Their LDL is 5.2 mmol/L, they have no premature CHD themselves, no cerebral or peripheral vascular disease, no tendon xanthoma, no corneal arcus before 45, no relevant first-degree family history beyond the mutation. Run the DLCN score.”
EHR automation FH flagging
“For this patient record — LDL 220 mg/dL, premature CHD present, a first-degree relative with LDL above the 95th percentile, no xanthoma, no arcus, no child with high LDL, no known DNA mutation — compute the Dutch Lipid Clinic Network familial hypercholesterolaemia score.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/dutch_fhWhen to prefer
Use this endpoint when you need to programmatically apply the adult Dutch Lipid Clinic Network (Nordestgaard 2013 Table 1) FH scoring algorithm — not the Simon Broome, MEDPED, or homozygous FH criteria — and all clinical findings have already been assessed by a clinician or extracted from structured EHR data. Ideal for automating lipid clinic workflows, EHR decision-support, or risk-stratification pipelines where LDL and family/clinical/DNA flags are available as structured inputs.
Side effects
- Missing required boolean flags returns a validation error
- Supplying both ldl_mmol_l and ldl_mg_dl simultaneously returns an error (exactly one must be provided)
- LDL value outside accepted range (mmol/L 1–20 or mg/dL 40–800) may be rejected or return an unexpected score
- Misclassified caller-assigned clinical findings (e.g., incorrect age cutoffs for premature CHD) produce an incorrect score — garbage-in-garbage-out with no server-side guard
- HTTP 402 returned if payment credentials are missing or invalid
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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