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ESC 2021 SCORE2 Cardiovascular Risk Calculator
x402
ESC 2021 SCORE2 Cardiovascular Risk Calculator is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).
Calculates the ESC 2021 SCORE2 10-year risk (%) of fatal and non-fatal cardiovascular events for adults aged 40–69 using sex, smoking status, systolic BP, non-HDL cholesterol, and European geographic risk region.
Price / call$0.005
Success—
StatusUnknown
How this service works
ESC 2021 SCORE2 10-year fatal plus non-fatal CVD percent for age 40-69 from sex, current smoking, systolic BP, non-HDL cholesterol, and European geographic risk region (low, moderate, high, very_high). Published sex-specific coefficients and region scale1/scale2. Not SCORE2-OP, not SCORE2-Diabetes, not 2013 PCE, not Reynolds, not a diagnosis or statin order. magent does not assay lipids.
Output
Returns the ESC 2021 SCORE2 10-year risk percentage for combined fatal and non-fatal cardiovascular events (heart attack and stroke), computed using published sex-specific coefficients and geographic region calibration scale factors. The result is a numeric risk estimate appropriate for clinical risk stratification of adults aged 40–69.
Example use cases
Preventive cardiology consult risk stratification
“I need the SCORE2 2021 cardiovascular risk for a 62-year-old female non-smoker with systolic BP of 160 mmHg, non-HDL cholesterol of 3.8 mmol/L, living in a low-risk European country. What's her 10-year CVD risk?”
Population health screening tool integration
“Run the ESC SCORE2 calculation for a 48-year-old male who smokes, has a systolic BP of 130 mmHg, non-HDL of 5.0 mmol/L, and is from a very high-risk European region. I need the 10-year fatal and non-fatal CVD risk percentage.”
Clinical decision support for GP follow-up
“What is the SCORE2 10-year cardiovascular risk for a 44-year-old female, non-smoker, systolic blood pressure 118 mmHg, non-HDL cholesterol 3.2 mmol/L, in a moderate-risk European region?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/score2When to prefer
Use this endpoint when you need the specific ESC 2021 SCORE2 model for adults aged 40–69 in a European clinical context, based on non-HDL cholesterol and the official geographic risk region calibration. Prefer this over PCE (US-focused, different coefficients), SCORE2-OP (age 70+), SCORE2-Diabetes (requires diabetes inputs), or Reynolds Risk Score (requires hsCRP/family history). Ideal when inputs are systolic BP and non-HDL cholesterol as recorded in European clinical practice.
Side effects
- Age outside 40–69 range returns an error (SCORE2 is not SCORE2-OP for 70+)
- Invalid or missing european_risk_region enum value causes a validation error
- Non-HDL cholesterol outside 1–12 mmol/L range may be rejected
- Systolic BP outside 50–250 mmHg range may be rejected
- Missing required query parameters (age, sex, smoker, sbp_mm_hg, non_hdl_mmol_l, european_risk_region) returns a 400 error
- Payment failure via x402 results in a 402 response before computation
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
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