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FDA Drug Shortage Detail & Therapeutic Alternative Cross-Check
x402
FDA Drug Shortage Detail & Therapeutic Alternative Cross-Check is a paid API for AI agents from aeml-x402.zeabur.app, paid per call via x402, $0.25/call, status unknown (last checked 2026-09-13).
Returns per-drug US FDA shortage status with NDC/manufacturer granularity, supply concentration metrics, and therapeutic-alternative shortage cross-check for a named drug
Price / call$0.25
Success—
StatusUnknown
How this service works
[3-LEG] Per-drug shortage chain, one drug (?entity=carboplatin): leading supply narrowing - available labelers against total listed -> current current FDA shortage status per NDC -> realized affected presentations (confirmation gate). A sequential chain, not one reading - confidence = how many legs are lit, in order. Sources: openFDA. Descriptive only, never a forecast or advice. No data -> 422 no_charge, not billed.
Output
A structured response containing: current FDA shortage status broken down by individual NDC codes and manufacturers, the supply concentration ratio (available manufacturers vs total listed), affected NDC count, dosage form and pharmacological classification, therapeutic-alternative cross-check showing whether same-ATC-class drugs are also in shortage (indicating exhausted backup), and a list of buyable alternative NDCs still on market per openFDA. Includes provenance, data age, and an honest disclosure note on data grade and scope.
Example use cases
Oncology procurement shortage triage
“Check the FDA shortage status for vincristine — break it down by NDC and manufacturer, tell me how many are still listed vs affected, and flag whether the therapeutic alternatives in the same ATC class are also in shortage so I know if our backup supply is gone.”
GPO buyer alternative sourcing check
“We need to source cisplatin urgently — can you look up its current FDA shortage detail, show me any NDCs still being sold and by which manufacturers, and tell me if other drugs in its class are also short?”
Hospital formulary risk assessment
“Run a shortage risk check on vancomycin: I want the supply concentration ratio of available vs total listed manufacturers, the status of each affected NDC, and whether ATC-class alternatives are also in shortage or still have open supply.”
Technical details
Endpoint
GEThttps://aeml-x402.zeabur.app/gauge/drug-detail-regionWhen to prefer
Choose this endpoint when you need granular, NDC-level FDA drug shortage intelligence for a specific drug — especially when you also need to know whether therapeutic alternatives in the same pharmacological class are also depleted, and which NDCs are still commercially available. Prefer this over general FDA shortage list scrapers when manufacturer-level supply concentration and ATC-class cross-check are required for hospital or GPO procurement decisions.
Side effects
- Unknown drug entity returns no legs or empty shortage data
- Drug name not matching openFDA or RxNav identifiers may yield null results
- Data freshness lag — FDA shortage list updates may not be real-time; provenance includes age_hours_now
- Therapeutic alternative cross-check limited to ATC class mapping available in NIH RxNav; uncommon drugs may have sparse class data
- Service returns honest data-grade disclaimer (screening-level, not decision-grade) — not a substitute for direct FDA or GPO verification
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| input | object | |
| output | object |
Output
Schema · Response
{
"type": "json"
}Tags
x402
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