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Grogan 2016 ATTRwt Cardiac Staging Calculator
x402
Grogan 2016 ATTRwt Cardiac Staging Calculator is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).
Calculates the Grogan 2016 staging score for wild-type transthyretin amyloid cardiomyopathy (ATTRwt) using NT-proBNP and cardiac troponin T values
Price / call$0.005
Success—
StatusUnknown
How this service works
Grogan 2016 ATTRwt staging: 1 point when NT-proBNP >3000 ng/L; 1 point when cardiac TnT >0.05 ng/mL. Stage I = 0, II = 1, III = 2. Equal to a cutoff does not score. Cohort 4-year OS I 57% / II 42% / III 18%; stage III median 20 months (labels, not a prediction). Troponin T only. Not Gillmore NAC (no eGFR). Not Mayo AL. Not NYHA. magent does not assay the biomarkers.
Output
Returns the Grogan 2016 ATTRwt stage (I, II, or III) based on the computed score (0, 1, or 2 points), with reference cohort 4-year overall survival rates: Stage I ~57%, Stage II ~42%, Stage III ~18% (median 20 months for Stage III). These are historical cohort labels, not individual predictions.
Example use cases
ATTRwt staging for cardiology consult
“I have a patient with wild-type ATTR cardiomyopathy — NT-proBNP is 3500 ng/L and cardiac troponin T is 0.04 ng/mL. What's their Grogan 2016 stage?”
Prognosis discussion with patient family
“Our patient's labs show NT-proBNP at 1800 ng/L and troponin T at 0.06 ng/mL. Can you calculate their ATTRwt Grogan stage and tell me the associated cohort survival data?”
Automated EHR biomarker staging pipeline
“Given NT-proBNP 3100 ng/L and cardiac troponin T 0.09 ng/mL, calculate the Grogan 2016 ATTRwt staging score and return the stage number.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/groganWhen to prefer
Use this endpoint when you need to apply the Grogan 2016 ATTRwt cardiac staging schema specifically — it uses only NT-proBNP and cardiac troponin T (not eGFR, troponin I, BNP, or NYHA class). Prefer this over Mayo AL staging (which is for AL amyloid), Gillmore NAC staging (which requires eGFR), and NYHA functional class. Suitable for automating staging in clinical workflows where biomarker values are already available.
Side effects
- Missing required query parameters (nt_probnp_ng_l or troponin_t_ng_ml) returns a validation error
- Values outside accepted ranges (NT-proBNP: 10–100000 ng/L; troponin T: 0.001–50 ng/mL) may be rejected
- Troponin I values provided instead of troponin T — endpoint only accepts troponin T and will not substitute
- Payment not provided or invalid x402 payment header results in 402 Payment Required
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
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