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HEMORR2HAGES Bleeding Risk Score Calculator
x402
HEMORR2HAGES Bleeding Risk Score Calculator is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Calculates the HEMORR2HAGES major bleeding risk score for atrial fibrillation patients on warfarin, returning a score (0–12) and estimated bleeds per 100 patient-years.
Price / call$0.005
Success—
StatusUnknown
How this service works
Gage 2006 HEMORR2HAGES (NRAF) AF major-bleed score: prior bleed 2; hepatic or renal, ethanol, malignancy, age >75, reduced platelet count or function, uncontrolled hypertension, anemia, genetic factors, excessive fall risk, and stroke each 1. Max 12. Warfarin major bleed per 100 patient-years: 0→1.9, 1→2.5, 2→5.3, 3→8.4, 4→10.4, ≥5→12.3. Not a medical device. Not a decision to start or stop anticoagulation. Not HAS-BLED, ORBIT, or ATRIA.
Output
Returns an integer HEMORR2HAGES score from 0 to 12 and the corresponding estimated rate of major warfarin-related bleeds per 100 patient-years (0→1.9, 1→2.5, 2→5.3, 3→8.4, 4→10.4, ≥5→12.3), based on the 11 clinical criteria from Gage 2006.
Example use cases
AFib anticoagulation risk stratification
“I have a 77-year-old AFib patient with a history of GI bleed and uncontrolled hypertension — no malignancy, no liver or kidney disease, no ethanol abuse, no anemia, no platelet issues, no genetic factors, no fall risk, no prior stroke. What's his HEMORR2HAGES score and estimated major bleed rate?”
Comparing bleeding risk across patients
“Can you compute HEMORR2HAGES scores for two patients? First: age 82, prior bleed, anemia, stroke, no other factors. Second: age 70, malignancy, ethanol abuse, reduced platelets, no prior bleed or stroke. Which one carries higher warfarin bleed risk?”
Documenting bleeding risk in clinical notes
“For my chart note, I need the HEMORR2HAGES score for a 65-year-old with hepatic disease and excessive fall risk but no prior bleed, no ethanol, no malignancy, no reduced platelets, no uncontrolled hypertension, no anemia, no genetic factors, and no stroke history.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/hemorr2hagesWhen to prefer
Use this endpoint when you need to compute the HEMORR2HAGES (Gage 2006) bleeding risk score specifically, as opposed to HAS-BLED, ORBIT, or ATRIA. It is ideal when the clinical context calls for the NRAF/HEMORR2HAGES framework, all 11 risk factor flags have already been clinically determined by the provider, and you need the corresponding published bleed-rate lookup per 100 patient-years. Not suitable as a substitute for HAS-BLED or when raw lab values (hemoglobin, platelet count) need to be auto-interpreted.
Side effects
- Missing required query parameters (age or any boolean flag) returns a 400 error
- Age outside the 18–120 range may be rejected or return unexpected results
- Boolean values passed as non-boolean types may cause schema validation errors
- Network or payment failure returns a 402 or 5xx response
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"path": "/api/calc/hemorr2hages",
"count": 2,
"items": [
{
"score": 0,
"formula": "hemorr2hages",
"citation": {
"id": "gage-2006",
"doi": "10.1016/j.ahj.2005.04.017",
"pmid": "16504638",
"title": "Clinical classification schemes for predicting hemorrhage: results from the National Registry of Atrial Fibrillation (NRAF)",
"source": "Am Heart J. 2006;151(3):713-719",
"authors": "Gage BF, Yan Y, Milligan PE, et al."
},
"age_years": 60,
"max_score": 12,
"components": [
{
"factor": "prior_bleed",
"points": 0,
"present": false
},
{
"factor": "hepatic_or_renal",
"points": 0,
"present": false
},
{
"factor": "ethanol",
"points": 0,
"present": false
},
{
"factor": "malignancy",
"points": 0,
"present": false
},
{
"value": 60,
"factor": "age_gt_75",
"points": 0,
"present": false
},
{
"factor": "reduced_platelet",
"points": 0,
"present": false
},
{
"factor": "uncontrolled_hypertension",
"points": 0,
"present": false
},
{
"factor": "anemia",
"points": 0,
"present": false
},
{
"factor": "genetic_factors",
"points": 0,
"present": false
},
{
"factor": "excessive_fall_risk",
"points": 0,
"present": false
},
{
"factor": "stroke",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"formula_expression": "HEMORR2HAGES = prior_bleed (2) + hepatic_or_renal (1) + ethanol (1) + malignancy (1) + age_gt_75 (1) + reduced_platelet (1) + uncontrolled_hypertension (1) + anemia (1) + genetic_factors (1) + excessive_fall_risk (1) + stroke (1); max 12; warfarin major bleed per 100 pt-years: 0=1.9, 1=2.5, 2=5.3, 3=8.4, 4=10.4, >=5=12.3",
"bleed_rate_per_100_pt_years": 1.9
},
{
"score": 0,
"formula": "hemorr2hages",
"citation": {
"id": "gage-2006",
"doi": "10.1016/j.ahj.2005.04.017",
"pmid": "16504638",
"title": "Clinical classification schemes for predicting hemorrhage: results from the National Registry of Atrial Fibrillation (NRAF)",
"source": "Am Heart J. 2006;151(3):713-719",
"authors": "Gage BF, Yan Y, Milligan PE, et al."
},
"age_years": 60,
"max_score": 12,
"components": [
{
"factor": "prior_bleed",
"points": 0,
"present": false
},
{
"factor": "hepatic_or_renal",
"points": 0,
"present": false
},
{
"factor": "ethanol",
"points": 0,
"present": false
},
{
"factor": "malignancy",
"points": 0,
"present": false
},
{
"value": 60,
"factor": "age_gt_75",
"points": 0,
"present": false
},
{
"factor": "reduced_platelet",
"points": 0,
"present": false
},
{
"factor": "uncontrolled_hypertension",
"points": 0,
"present": false
},
{
"factor": "anemia",
"points": 0,
"present": false
},
{
"factor": "genetic_factors",
"points": 0,
"present": false
},
{
"factor": "excessive_fall_risk",
"points": 0,
"present": false
},
{
"factor": "stroke",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"formula_expression": "HEMORR2HAGES = prior_bleed (2) + hepatic_or_renal (1) + ethanol (1) + malignancy (1) + age_gt_75 (1) + reduced_platelet (1) + uncontrolled_hypertension (1) + anemia (1) + genetic_factors (1) + excessive_fall_risk (1) + stroke (1); max 12; warfarin major bleed per 100 pt-years: 0=1.9, 1=2.5, 2=5.3, 3=8.4, 4=10.4, >=5=12.3",
"bleed_rate_per_100_pt_years": 1.9
}
]
}
}Tags
x402
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