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HFA-ICOS Anthracycline Cardiovascular Risk Calculator
x402
HFA-ICOS Anthracycline Cardiovascular Risk Calculator is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).
Calculates the Lyon 2020 HFA-ICOS baseline cardiovascular risk level (low/medium/high/very_high) before anthracycline chemotherapy based on patient risk factors
Price / call$0.005
Success—
StatusUnknown
How this service works
Lyon 2020 HFA-ICOS baseline cardiovascular risk before anthracycline chemotherapy. Returns risk_level low, medium, high, or very_high from published Very high, High, Medium 2, and Medium 1 factors, plus medium_points and the paper's expert-opinion cardiotoxicity_guide. Age and LVEF use the highest matching printed band only. Caller assigns labs and BMI >30. magent does not examine the patient or read imaging. Not a medical device or treatment order.
Output
Returns a JSON object with: risk_level (one of low, medium, high, very_high per Lyon 2020 HFA-ICOS classification), medium_points (integer count of Medium 1/Medium 2 factors accumulated), and cardiotoxicity_guide (the paper's expert-opinion guidance text corresponding to the computed risk tier).
Example use cases
Pre-chemo cardiac risk screen
“I need to know this breast cancer patient's HFA-ICOS cardiovascular risk before we start her on doxorubicin — she's 68 years old, LVEF is 55%, she has hypertension and is obese (BMI >30), no prior heart failure, no valvular disease, no MI or revascularization, no prior anthracyclines, no chest radiation, troponin and BNP are normal, no diabetes, no CKD, non-smoker, and no previous non-anthracycline chemo.”
High-risk flag for elderly patient
“Can you run the Lyon 2020 HFA-ICOS anthracycline risk score for an 81-year-old patient with LVEF of 48%, prior coronary revascularization, elevated troponin, hypertension, and diabetes — no heart failure, no valvular disease, no angina, no prior anthracyclines, no chest RT, BNP is normal, no CKD, no prior non-anthracycline chemo, current smoker, not obese?”
Oncology trial enrollment screening
“We're enrolling patients in an anthracycline trial and need to document baseline HFA-ICOS risk category — this patient is 58 years old, LVEF 60%, no heart failure, no valvular disease, no MI, no angina, no prior anthracyclines, no chest RT, troponin normal, BNP normal, no hypertension, no diabetes, no CKD, no prior non-anthracycline chemo, non-smoker, not obese.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/hfa_icos_anthracyclineWhen to prefer
Use this endpoint when you need to programmatically apply the Lyon 2020 HFA-ICOS baseline cardiovascular risk stratification for a patient about to receive anthracycline chemotherapy, especially in agentic clinical decision-support workflows, EHR integrations, or oncology trial screening pipelines. Caller must pre-assign lab-derived flags (troponin, BNP, HbA1c, eGFR, BMI) since the endpoint does not compute them from raw values. Prefer this over generic risk calculators when the specific HFA-ICOS framework and its expert-opinion cardiotoxicity guidance text are required.
Side effects
- Missing required query parameters returns a validation error
- age_years outside 18-100 range or lvef_percent outside 10-80 range returns a validation error
- Non-boolean values for flag fields return a schema error
- Network or server errors return HTTP 5xx
- Payment not provided or insufficient returns HTTP 402
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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