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IMWG Multiple Myeloma Response Classification (Kumar 2016)
x402
IMWG Multiple Myeloma Response Classification (Kumar 2016) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Classifies myeloma treatment response per Kumar 2016 IMWG criteria (PD, sCR, CR, VGPR, PR, MR, or SD) from caller-assigned boolean flags for serum/urine M-protein, IFE, bone marrow, and FLC findings.
Price / call$0.005
Success—
StatusUnknown
How this service works
Kumar 2016 IMWG measurable serum+urine M-protein response. First-match PD, sCR, CR, VGPR, PR, MR, or SD from caller-assigned flags. sCR is CR plus normal FLC ratio and no clonal BM cells by IHC. CR is negative serum and urine IFE, no plasmacytomas, and BMPC <5%. VGPR is electrophoresis-negative or ≥90% serum M-protein reduction with urine M-protein <100 mg/24 h. Not a diagnosis. Not MRD. Not FLC-only. magent does not assay labs.
Output
Returns the first-matching IMWG Kumar 2016 response category: one of PD, sCR, CR, VGPR, PR, MR, or SD, determined by evaluating the caller-supplied boolean flags in priority order. Does not return MRD status, FLC-only response, or laboratory values.
Example use cases
Automated trial response adjudication
“For our myeloma trial data pipeline, classify the IMWG response for a patient where PD is false, serum IFE is negative, urine IFE is negative, no plasmacytomas, bone marrow plasma cells less than 5%, FLC ratio is normal, and no clonal cells on IHC — is this sCR or CR?”
CR vs VGPR determination at interim analysis
“I need to determine if this myeloma patient hit VGPR: PD flag false, electrophoresis is negative, serum M-protein reduction is at least 90%, and urine M-protein is below 100 mg per 24 hours — what does IMWG 2016 say?”
Progressive disease flag check in myeloma follow-up
“My oncology app needs to label this patient's response — PD flag is true based on my M-protein serial calculations — can you confirm the IMWG response category comes back as PD regardless of any other flags?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/imwg_responseWhen to prefer
Use this endpoint when you have already computed or extracted IMWG boolean indicators from lab data and need a standardized, auditable Kumar 2016 response category label — particularly for clinical trial data pipelines, oncology EMR automation, or decision-support tools that must document IMWG response per protocol. Do not use if you need MRD assessment, FLC-only response classification, or if you expect the endpoint to compute M-protein trends from raw serial values.
Side effects
- Missing required boolean flags returns a validation error
- Ambiguous flag combinations (e.g. PD true plus CR flags true) resolve to PD by priority — not an error but may surprise callers
- Endpoint does not validate biological plausibility of flag combinations
- Does not handle FLC-only disease or MRD assessments — will not return meaningful results in those contexts
- Network or payment (x402) failure returns non-200 status
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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