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IPS-E Score Calculator (Condoluci 2020) for Early-Stage CLL
x402
IPS-E Score Calculator (Condoluci 2020) for Early-Stage CLL is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).
Computes the Condoluci 2020 IPS-E time-to-first-treatment prognostic score (0–3) for asymptomatic early-stage chronic lymphocytic leukemia using three caller-assigned binary/numeric inputs.
Price / call$0.005
Success—
StatusUnknown
How this service works
Condoluci 2020 IPS-E for asymptomatic early-stage chronic lymphocytic leukemia: unmutated IGHV 1, ALC >15 ×10^9/L 1, palpable lymph nodes 1; max 3. Low 0, intermediate 1, high 2–3. Time-to-first-treatment score, not a treatment start order; not CLL-IPI, Rai, or Binet. magent does not assay IGHV, count lymphocytes, or palpate nodes.
Output
Returns an IPS-E integer score from 0 to 3, where 0 = low risk, 1 = intermediate risk, and 2–3 = high risk for time to first treatment in asymptomatic early-stage CLL, based on the three Condoluci 2020 criteria.
Example use cases
Risk-stratify newly diagnosed CLL patient
“I have a patient just diagnosed with asymptomatic early-stage CLL. Their IGHV is unmutated, ALC is 22 ×10^9/L, and they have no palpable lymph nodes. What is their IPS-E score and risk category?”
Estimate time-to-treatment for low-risk CLL
“My CLL patient has mutated IGHV, an ALC of 12 ×10^9/L, and no palpable lymph nodes. Run the Condoluci IPS-E score so I can tell them how urgent treatment might be.”
High-risk CLL prognostic counseling
“Can you compute the IPS-E score for a patient with unmutated IGHV, ALC of 30 ×10^9/L, and palpable lymph nodes — I need the score and whether this puts them in the high-risk group.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/ips_eWhen to prefer
Use this endpoint when you need a fast, standardized Condoluci 2020 IPS-E score for asymptomatic early-stage CLL and already have the three required clinical values (IGHV mutation status, ALC, palpable lymph nodes) pre-assessed. This is specifically for prognostic time-to-first-treatment stratification in early CLL, not for CLL-IPI, Rai staging, or Binet staging. Prefer this over a general LLM computation when you need a reproducible, published-algorithm result.
Side effects
- Missing required query parameters (ighv_unmutated, alc_k_ul, palpable_lymph_nodes) returns a 400 error
- ALC value outside the accepted range (0.1–500 ×10^9/L) may return validation error
- Payment not provided or invalid x402 payment header causes 402 response
- Caller misclassifying clinical inputs (IGHV status, ALC, node exam) before submission — the API trusts caller-assigned values without verification
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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