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ISTH Overt DIC Score (Taylor 2001)
x402
ISTH Overt DIC Score (Taylor 2001) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Calculates the ISTH Scientific and Standardisation Committee overt disseminated intravascular coagulation (DIC) score from four laboratory values, returning a total score and compatibility verdict.
Price / call$0.005
Success—
StatusUnknown
How this service works
Taylor 2001 ISTH SSC overt DIC (four lab items; max 8). Platelets >=100=0, 50-<100=1, <50=2. fibrin_related_marker none/moderate/strong = 0/2/3 (caller-assigned; magent does not grade D-dimer). PT sec above ULN <3=0, >=3 and <6=1, >=6=2. Fibrinogen >=1.0 g/L=0, <1.0=1 (XOR g/L or mg/dL÷100). Band <5 not compatible with overt DIC; >=5 compatible. Not a diagnosis. Not the non-overt serial score.
Output
Returns the total ISTH overt DIC score (0–8), individual sub-scores for each of the four laboratory components, and a binary interpretation: score ≥5 is compatible with overt DIC, score <5 is not compatible. Does not issue a clinical diagnosis.
Example use cases
ICU sepsis DIC screen
“My ICU patient with sepsis has platelets of 45, PT prolonged 7 seconds above normal, fibrinogen 0.7 g/L, and D-dimer is markedly elevated so I'd call the fibrin-related marker strong — what's the ISTH overt DIC score?”
Post-surgical coagulopathy evaluation
“Can you calculate the Taylor 2001 DIC score for a post-op patient? Platelets are 110, PT is only 2 seconds above the lab's upper limit, fibrinogen is 1.2 g/L, and fibrin marker is moderate.”
Obstetric hemorrhage DIC check
“I have an obstetric patient with suspected consumptive coagulopathy — platelets 55, PT prolonged 3.5 seconds above ULN, fibrinogen 90 mg/dL, and fibrin marker is moderate. What does the ISTH overt DIC score come back as?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/isth_dicWhen to prefer
Use this endpoint when you need a standardized, reproducible ISTH overt DIC score per the Taylor 2001 algorithm for adult patients, particularly in ICU, hematology, or obstetric workflows. Prefer this over manual calculation to eliminate arithmetic errors and ensure correct boundary handling (e.g. exactly 50 platelets scores 1, not 0). Do not use for the non-overt serial DIC score or for pediatric-specific DIC scoring systems.
Side effects
- Missing required parameters (platelets, fibrin_related_marker, or pt_prolongation_sec) returns a validation error
- Providing both fibrinogen_g_l and fibrinogen_mg_dl simultaneously returns an error (XOR fields)
- Out-of-range values (e.g. platelets >2000 or PT prolongation >30) may be rejected
- Invalid fibrin_related_marker enum value (must be none, moderate, or strong) returns an error
- Network or payment failure results in no score returned
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"path": "/api/calc/isth_dic",
"count": 2,
"items": [
{
"score": 0,
"formula": "isth_dic",
"citation": {
"id": "taylor-2001",
"doi": "10.1055/s-0037-1616068",
"pmid": "11816725",
"title": "Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation",
"source": "Thromb Haemost. 2001;86(5):1327-1330",
"authors": "Taylor FB Jr, Toh CH, Hoots WK, Wada H, Levi M"
},
"max_score": 8,
"components": [
{
"value": 180,
"factor": "platelets",
"points": 0,
"present": false
},
{
"value": "none",
"factor": "fibrin_related_marker",
"points": 0,
"present": false
},
{
"value": 1,
"factor": "pt_prolongation",
"points": 0,
"present": false
},
{
"value": 2.5,
"factor": "fibrinogen",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"isth_dic_band": "<5",
"fibrinogen_g_l": 2.5,
"platelets_10e9_l": 180,
"formula_expression": "ISTH overt DIC = platelets_10e9_l (>=100 → 0; 50 to <100 → 1; <50 → 2) + fibrin_related_marker (none 0, moderate 2, strong 3) + pt_prolongation_sec (<3 → 0; >=3 and <6 → 1; >=6 → 2) + fibrinogen_g_l (>=1.0 → 0; <1.0 → 1); max 8; bands <5 / >=5",
"pt_prolongation_sec": 1,
"fibrin_related_marker": "none"
},
{
"score": 0,
"formula": "isth_dic",
"citation": {
"id": "taylor-2001",
"doi": "10.1055/s-0037-1616068",
"pmid": "11816725",
"title": "Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation",
"source": "Thromb Haemost. 2001;86(5):1327-1330",
"authors": "Taylor FB Jr, Toh CH, Hoots WK, Wada H, Levi M"
},
"max_score": 8,
"components": [
{
"value": 180,
"factor": "platelets",
"points": 0,
"present": false
},
{
"value": "none",
"factor": "fibrin_related_marker",
"points": 0,
"present": false
},
{
"value": 1,
"factor": "pt_prolongation",
"points": 0,
"present": false
},
{
"value": 2.5,
"factor": "fibrinogen",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"isth_dic_band": "<5",
"fibrinogen_g_l": 2.5,
"platelets_10e9_l": 180,
"formula_expression": "ISTH overt DIC = platelets_10e9_l (>=100 → 0; 50 to <100 → 1; <50 → 2) + fibrin_related_marker (none 0, moderate 2, strong 3) + pt_prolongation_sec (<3 → 0; >=3 and <6 → 1; >=6 → 2) + fibrinogen_g_l (>=1.0 → 0; <1.0 → 1); max 8; bands <5 / >=5",
"pt_prolongation_sec": 1,
"fibrin_related_marker": "none"
}
]
}
}Tags
x402
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