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Khorana 2008 VTE Risk Score Calculator
x402
Khorana 2008 VTE Risk Score Calculator is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Computes the Khorana 2008 venous thromboembolism (VTE) risk score for cancer patients about to receive chemotherapy, returning a numeric score and low/intermediate/high risk category.
Price / call$0.005
Success—
StatusUnknown
How this service works
Khorana 2008 Blood predictive model for chemotherapy-associated thrombosis: very_high site (stomach or pancreas) 2, high (lung, lymphoma, gynecologic, bladder, testicular) 1, other 0; platelets >=350 1; hemoglobin <10 g/dL or ESA 1 (once); WBC >11 x10^9/L 1; BMI>=35 caller flag 1. Max 6. 0 low; 1-2 intermediate; >=3 high. Not a diagnosis. Not Padua or Caprini. Caller assigns cancer site; magent does not compute BMI.
Output
Returns the total Khorana score (0–6), the risk category (low for 0, intermediate for 1–2, high for ≥3), and a breakdown of points assigned to each criterion (cancer site, platelets, hemoglobin/ESA, WBC, BMI). Does not make diagnostic or treatment decisions.
Example use cases
Pre-chemo thrombosis triage in oncology workflow
“My patient has lung cancer (high Khorana site), platelets at 355 ×10⁹/L, hemoglobin 10.8 g/dL, WBC 9.2 ×10³/µL, not on ESA, and BMI is 32 — what's their Khorana score before we start chemo?”
High-risk flag for stomach cancer patient
“Score this stomach cancer patient for chemo-associated clot risk: platelets 290, hemoglobin 8.5 g/dL, WBC 14 ×10³/µL, they are on an erythropoiesis-stimulating agent, and BMI is over 35.”
Low-risk confirmation for lymphoma patient
“Can you run the Khorana 2008 score for a lymphoma patient — high site class, platelets 210, hemoglobin 12 g/dL, WBC 8.5 ×10³/µL, no ESA use, and BMI under 35 — I want to confirm they're low risk before chemo?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/khoranaWhen to prefer
Use this endpoint when you need to compute the validated Khorana 2008 score specifically — not Padua, Caprini, or other VTE risk tools. Ideal when the caller has already classified cancer site per Khorana categories and has pre-chemotherapy lab values (platelets, hemoglobin, WBC) available. Choose this over a general clinical calculator when you need structured per-criterion point attribution and a machine-readable risk tier for downstream workflow logic.
Side effects
- Missing required parameters (cancer_site, platelets_10e9_l, erythropoiesis_stimulating_agent, bmi_ge_35) returns a validation error
- Providing both hemoglobin_g_dl and hemoglobin_g_l simultaneously returns an error
- Out-of-range values (e.g. platelets outside 1–2000) rejected with range error
- Invalid cancer_site string (not 'very_high', 'high', or 'other') causes a parameter error
- Providing both wbc_ul and wbc_k_ul simultaneously may cause ambiguity or error
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"path": "/api/calc/khorana",
"count": 2,
"items": [
{
"score": 0,
"wbc_ul": 8000,
"formula": "khorana",
"citation": {
"id": "khorana-2008",
"doi": "10.1182/blood-2007-10-116327",
"title": "Development and validation of a predictive model for chemotherapy-associated thrombosis",
"source": "Blood. 2008;111(10):4902-4907",
"authors": "Khorana AA, Kuderer NM, Culakova E, Lyman GH, Francis CW"
},
"bmi_ge_35": false,
"max_score": 6,
"components": [
{
"value": "other",
"factor": "cancer_site",
"points": 0,
"present": false
},
{
"value": 200,
"factor": "platelets",
"points": 0,
"present": false
},
{
"value": {
"hemoglobin_g_dl": 12,
"erythropoiesis_stimulating_agent": false
},
"factor": "hemoglobin_or_esa",
"points": 0,
"present": false
},
{
"value": 8000,
"factor": "wbc",
"points": 0,
"present": false
},
{
"factor": "bmi_ge_35",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"cancer_site": "other",
"khorana_risk": "low",
"hemoglobin_g_dl": 12,
"platelets_10e9_l": 200,
"formula_expression": "Khorana = cancer_site (very_high 2, high 1, other 0) + (platelets>=350) + (hemoglobin<10 g/dL or ESA) + (wbc>11 x10^9/L) + (BMI>=35); max 6; 0 low, 1-2 intermediate, >=3 high",
"erythropoiesis_stimulating_agent": false
},
{
"score": 0,
"wbc_ul": 8000,
"formula": "khorana",
"citation": {
"id": "khorana-2008",
"doi": "10.1182/blood-2007-10-116327",
"title": "Development and validation of a predictive model for chemotherapy-associated thrombosis",
"source": "Blood. 2008;111(10):4902-4907",
"authors": "Khorana AA, Kuderer NM, Culakova E, Lyman GH, Francis CW"
},
"bmi_ge_35": false,
"max_score": 6,
"components": [
{
"value": "other",
"factor": "cancer_site",
"points": 0,
"present": false
},
{
"value": 200,
"factor": "platelets",
"points": 0,
"present": false
},
{
"value": {
"hemoglobin_g_dl": 12,
"erythropoiesis_stimulating_agent": false
},
"factor": "hemoglobin_or_esa",
"points": 0,
"present": false
},
{
"value": 8000,
"factor": "wbc",
"points": 0,
"present": false
},
{
"factor": "bmi_ge_35",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"cancer_site": "other",
"khorana_risk": "low",
"hemoglobin_g_dl": 12,
"platelets_10e9_l": 200,
"formula_expression": "Khorana = cancer_site (very_high 2, high 1, other 0) + (platelets>=350) + (hemoglobin<10 g/dL or ESA) + (wbc>11 x10^9/L) + (BMI>=35); max 6; 0 low, 1-2 intermediate, >=3 high",
"erythropoiesis_stimulating_agent": false
}
]
}
}Tags
x402
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