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magent irAE Colitis Grade Calculator (Brahmer 2018)
x402
magent irAE Colitis Grade Calculator (Brahmer 2018) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).
Calculates immune-related adverse event (irAE) colitis grade (1–4) per Brahmer 2018 ASCO Table 2.1 and returns the corresponding ICI (immune checkpoint inhibitor) management action.
Price / call$0.005
Success—
StatusUnknown
How this service works
Brahmer 2018 ASCO Table 2.1 irAE colitis grade from stools_over_baseline (0-40) and four caller-assigned flags. First-match: grade 4 if life_threatening; else 3 if stools >= 7 or incontinence or hospitalization_indicated or limiting_self_care; else 2 if stools >= 4; else 1. Returns icpi_action continue, hold, hold_consider_discontinue_ctla4, or permanently_discontinue. Ostomy-output bands not implemented. magent does not count stools. Not a medical device, not a diagnosis, not a steroid dose.
Output
Returns the irAE colitis grade (1–4) computed by first-match logic from the Brahmer 2018 ASCO Table 2.1 algorithm, plus the recommended ICI management action string: one of 'continue', 'hold', 'hold_consider_discontinue_ctla4', or 'permanently_discontinue'. Does not include steroid dosing, patient examination, or stool counting.
Example use cases
Automate ICI colitis grading in oncology workflow
“I have a patient on anti-PD-1 therapy with 8 stools over baseline, no incontinence, hospitalization is indicated, not limiting self-care, and not life-threatening — what irAE colitis grade are they and should immunotherapy be held or discontinued?”
Life-threatening colitis flagged by clinician
“My patient has life-threatening colitis consequences requiring urgent intervention — regardless of stool count, what grade does that make the irAE colitis and what does Brahmer 2018 say to do with their checkpoint inhibitor?”
Mild diarrhea on immunotherapy
“A patient on checkpoint inhibitor therapy has 3 stools over baseline, no incontinence, no hospitalization needed, not limiting self-care, and not life-threatening — what colitis grade is this and can they continue treatment?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/irae_colitisWhen to prefer
Choose this endpoint when you need a fast, rule-based irAE colitis grade and ICI action recommendation strictly following Brahmer 2018 ASCO Table 2.1 — particularly useful in agentic oncology workflows where caller-assigned clinical flags (incontinence, hospitalization, life-threatening) are already available and you need a structured, auditable grading output without LLM interpretation. Not appropriate when ostomy-output banding is required, steroid dosing is needed, or a licensed clinical judgment is sought.
Side effects
- Missing required query parameters returns a validation error
- stools_over_baseline outside integer range 0–40 may cause rejection or unexpected behavior
- Ostomy-output increase is not supported as an input and will not be graded correctly
- Conflicting flags (e.g., life_threatening=false but all grade-3 flags false and stools<4) defaults to grade 1
- Payment failure (402) if USDC balance is insufficient for the $0.005 per-call fee
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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