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magent irAE Pneumonitis Grader (Brahmer 2018)
x402
magent irAE Pneumonitis Grader (Brahmer 2018) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).
Classifies immune checkpoint inhibitor-related pneumonitis severity into CTCAE G1–G4 grades per Brahmer 2018 ASCO Table 3.1 and returns the corresponding ICPi management recommendation (hold or permanently discontinue).
Price / call$0.005
Success—
StatusUnknown
How this service works
Brahmer 2018 ASCO Table 3.1 irAE pneumonitis. First-match: G4 life-threatening respiratory compromise; else G3 hospitalization, oxygen, limiting self-care, or all lobes/>50%; else G2 symptomatic, >1 lobe, 25-50% parenchyma, or limiting instrumental ADL; else G1. ICPi: hold_if_radiographic_progression (G1), hold (G2), permanently_discontinue (G3-4). Caller-assigned flags. magent does not read CT or pulse oximetry. Not SITC 2021, not a CTCAE instrument, not a diagnosis, not a steroid dose.
Output
Returns the computed irAE pneumonitis severity grade (G1, G2, G3, or G4) based on Brahmer 2018 ASCO Table 3.1 first-match logic, along with the corresponding ICPi management recommendation: hold_if_radiographic_progression (G1), hold (G2), or permanently_discontinue (G3–G4). The endpoint does not perform diagnosis, read imaging, assess oxygen saturation, or prescribe steroids.
Example use cases
Oncology clinical triage for irAE
“I have a cancer patient on pembrolizumab who is symptomatic with pneumonitis affecting two lobes and 30% of parenchyma, limiting instrumental ADLs but not needing hospitalization or oxygen — run Brahmer 2018 Table 3.1 pneumonitis grading and tell me the ICPi recommendation.”
Automated irAE flagging in EMR pipeline
“Flag this immunotherapy patient: they have life-threatening respiratory compromise from suspected checkpoint inhibitor pneumonitis involving all lobes — grade the pneumonitis and give me the management recommendation.”
Borderline G1 radiographic-only case
“My patient on nivolumab has no symptoms, no hospitalization, no oxygen needs, no ADL limitations, and the pneumonitis looks confined to one lobe under 25% — apply Brahmer 2018 grading and tell me if I need to hold the checkpoint inhibitor.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/irae_pneumonitisWhen to prefer
Use this endpoint when you need to apply specifically the Brahmer 2018 ASCO pneumonitis grading algorithm (Table 3.1) to caller-assigned clinical flags for ICPi-related pneumonitis. Prefer this over manual lookup when building automated oncology workflows, irAE dashboards, or clinical decision-support pipelines. Do not use if you need SITC 2021 guidance, CTCAE scoring as an instrument, imaging interpretation, or steroid dosing recommendations.
Side effects
- Missing required boolean query parameters returns a validation error
- Ambiguous or missing flags may result in incorrect grade if caller-assigned inputs do not reflect clinical truth
- Endpoint applies only Brahmer 2018 Table 3.1 logic — results differ from SITC 2021 or other irAE grading frameworks
- Non-pneumonitis irAE types (colitis, hepatitis, etc.) are out of scope and will not return meaningful grades
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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