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Magent Neonatal Early-Onset Sepsis (EOS) Risk Calculator
x402
Magent Neonatal Early-Onset Sepsis (EOS) Risk Calculator is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).
Calculates neonatal early-onset sepsis risk using Puopolo 2011 prior probability (from maternal/obstetric factors) combined with Escobar 2014 Bayesian posterior update from clinical exam category
Price / call$0.005
Success—
StatusUnknown
How this service works
Puopolo 2011 neonatal early-onset sepsis prior at birth (≥34 weeks) from maternal temperature, gestational age, ROM, GBS, and antibiotic timing, then Escobar 2014 posterior after a caller-assigned well, equivocal, or ill exam. Incidence intercepts 0.3-0.6 per 1000 replace the printed 47.8398 constant. Not a sepsis diagnosis or antibiotic order. magent does not examine the infant.
Output
Returns a prior EOS probability (Puopolo 2011 logistic model from gestational age, maternal temperature, ROM duration, GBS status, and antibiotic timing) and a Bayesian posterior probability updated by the Escobar 2014 exam category (well, equivocal, or ill), expressed as a risk per 1000 or similar numeric output. This is a clinical decision-support estimate, not a diagnosis or antibiotic order.
Example use cases
Late preterm infant with maternal fever
“Calculate the early-onset sepsis risk for a 36-week baby: mom had a peak intrapartum temp of 101.2°F, ROM for 24 hours, GBS positive, received GBS-specific antibiotics 3 hours before delivery so gbs_or_any_abx_2h is true, no broad-spectrum antibiotics, infant looks well on exam, and our local incidence is 0.5 per 1000.”
Term infant with prolonged ROM and unknown GBS
“What's the neonatal sepsis posterior probability for a 39-week and 4-day infant — gestational age 39.57 weeks — with ROM of 48 hours, unknown GBS status, maternal temp 99.1°F, no antibiotics given, and the newborn exam is equivocal? Use a local EOS incidence of 0.3 per 1000.”
Near-term infant appearing ill after GBS-positive delivery
“Run the Puopolo-Escobar EOS calculator for a 34.5-week newborn who looks ill on exam: mother was GBS positive, peak temp 102.4°F, membranes ruptured 12 hours ago, broad-spectrum antibiotics started 5 hours before delivery (so broad_spectrum_abx_4h is true), and our hospital EOS rate is 0.6 per 1000.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/neonatal_eosWhen to prefer
Use this endpoint when you need a validated, two-stage Bayesian neonatal EOS risk estimate that combines Puopolo 2011 obstetric prior probability with Escobar 2014 clinical exam posterior update. Prefer this over generic sepsis scoring tools when the patient is a late-preterm or term neonate (≥34 weeks) and you have maternal fever, GBS status, ROM duration, antibiotic timing, and a clinical exam category available. Not suitable for infants under 34 weeks gestation or for generating antibiotic orders.
Side effects
- Gestational age below 34 weeks is rejected (Puopolo 2011 scope)
- eos_incidence_per_1000 values other than 0.3, 0.4, 0.5, or 0.6 are rejected (only published intercepts accepted)
- maternal_temp_f outside 94.0–108.0°F range returns an error
- rom_hours outside 0–240 returns an error
- gestational_age_weeks outside 34.0–43.0 returns an error
- Missing required query parameters return a validation error
- Invalid enum values for gbs or clinical_category return an error
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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