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Magent SMM 2/20/20 Risk Calculator (Lakshman 2018)
x402
Magent SMM 2/20/20 Risk Calculator (Lakshman 2018) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Calculates smoldering multiple myeloma (SMM) progression risk score using the Lakshman 2018 2/20/20 model from caller-supplied BMPC percentage, serum M-protein, and FLC ratio
Price / call$0.005
Success—
StatusUnknown
How this service works
Lakshman 2018 2/20/20 smoldering myeloma risk: one point each for BMPC >20%, serum M-protein >2 g/dL, and involved/uninvolved FLC ratio >20 (strict greater-than). 0 factors low (median TTP 110 months), 1 intermediate (68), 2 or 3 high (29). Not Mayo 70/20, not PETHEMA, not myeloma ISS, not a treatment order. BMPC 10-59 and FLC 0.01-99.9 (IMWG 2014 SLiM myeloma is rejected). magent does not assay marrow, M-protein, or free light chains.
Output
Returns the computed 2/20/20 integer risk score (0, 1, 2, or 3), the corresponding risk category (low for 0, intermediate for 1, high for 2-3), and the associated median time-to-progression in months (110, 68, or 29 respectively). Inputs outside valid SMM ranges (BMPC <10 or ≥60, FLC ratio ≥100) are rejected as myeloma or out-of-scope.
Example use cases
Hematology clinic SMM risk triage
“I just reviewed a smoldering myeloma patient: BMPC is 45%, M-protein is 1.5 g/dL, and FLC ratio is 18. Can you run the Lakshman 2/20/20 score and tell me if they're low, intermediate, or high risk and what the expected time to progression is?”
Research cohort risk stratification
“For our SMM study cohort entry, apply the 2/20/20 Lakshman 2018 model to these values: bone marrow plasma cells 22%, serum M-protein 2.1 g/dL, FLC ratio 30. What risk group does this patient fall into?”
Clinical note generation for oncology EHR
“Before I write up this patient's note, calculate their smoldering myeloma 2/20/20 risk score — BMPC is 15%, M-protein is 3.2 g/dL, and FLC ratio is 12 — and give me the risk tier and median time-to-progression figure.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/smm_22020When to prefer
Use this endpoint when you need to apply specifically the Lakshman 2018 2/20/20 risk model to a smoldering multiple myeloma patient with known BMPC%, serum M-protein, and FLC ratio values. Prefer this over Mayo 70/20 or PETHEMA calculators when the clinical context calls for the 2/20/20 stratification scheme. Do not use for confirmed myeloma (CRAB criteria or SLiM-positive), for treatment ordering, or if you need actual lab assay results — this calculator only scores caller-supplied values.
Side effects
- BMPC ≥60% rejected — meets IMWG 2014 SLiM myeloma threshold, not SMM
- FLC ratio ≥100 rejected — meets myeloma criteria, out of SMM scoring range
- BMPC <10% rejected — below SMM floor
- Missing required query parameters (bmpc_percent, m_protein_g_dl, flc_ratio) returns error
- Values at exactly 20 (BMPC), 2 (M-protein), or 20 (FLC) score 0 points each (strict greater-than rule)
- Non-numeric or out-of-range parameter types return validation error
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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