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Magent Sodium Deficit Calculator (Adrogué–Madias)
x402
Magent Sodium Deficit Calculator (Adrogué–Madias) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Calculates sodium deficit in mmol using the Adrogué–Madias total body water formula based on patient sex, weight, and measured serum sodium.
Price / call$0.005
Success—
StatusUnknown
How this service works
Sodium deficit from weight, sex, and measured Na using Adrogué–Madias TBW (0.6 male / 0.5 female). Deterministic published arithmetic with citation; not a sodium infusion protocol.
Output
Returns the calculated sodium deficit in mmol based on Adrogué–Madias total body water (0.6 × weight for males, 0.5 × weight for females), the measured serum sodium, and the target serum sodium (default 140 mmol/L), along with a citation to the published formula.
Example use cases
ICU hyponatremia assessment
“I have a female ICU patient, 65 kg, with a serum sodium of 112 mmol/L. What's her sodium deficit if we're targeting 120 mmol/L?”
ED sodium correction planning
“Can you calculate the sodium deficit for a 90 kg male patient who came in with a sodium of 122 mmol/L? Use the default target of 140.”
Nephrology consult documentation
“I need the Adrogué–Madias sodium deficit for a 55 kg female with a measured Na of 128 mmol/L and a target Na of 135 mmol/L.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/sodium_deficitWhen to prefer
Use this endpoint when you need a deterministic, citation-backed sodium deficit calculation using the Adrogué–Madias TBW formula for hyponatremic patients. Prefer this over manual calculation when integrating into clinical decision-support workflows or documentation pipelines where formula accuracy and provenance matter. This is a pure arithmetic endpoint — not a treatment protocol or infusion rate calculator.
Side effects
- Missing required sex or sodium_mmol_l parameters returns a 400 error
- Serum sodium outside the valid hyponatremia range (90–135 mmol/L) may return a validation error
- Neither weight_kg nor weight_lb provided may result in a missing weight error
- Target sodium below measured sodium returns an error (target must exceed measured Na)
- Target sodium outside 120–150 mmol/L range may be rejected
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"path": "/api/calc/sodium_deficit",
"count": 2,
"items": [
{
"sex": "male",
"tbw_l": 42,
"formula": "adrogue_madias",
"citation": {
"id": "adrogue-madias-hyponatremia-2000",
"doi": "10.1056/NEJM200005253422107",
"title": "Hyponatremia",
"source": "N Engl J Med. 2000;342(21):1581-1589",
"authors": "Adrogué HJ, Madias NE"
},
"weight_kg": 70,
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"sodium_mmol_l": 120,
"desired_na_mmol_l": 140,
"formula_expression": "TBW_L = 0.6 * weight_kg (male) or 0.5 * weight_kg (female); sodium_deficit_mmol = TBW_L * (desired_na_mmol_l - sodium_mmol_l)",
"sodium_deficit_mmol": 840
},
{
"sex": "male",
"tbw_l": 42,
"formula": "adrogue_madias",
"citation": {
"id": "adrogue-madias-hyponatremia-2000",
"doi": "10.1056/NEJM200005253422107",
"title": "Hyponatremia",
"source": "N Engl J Med. 2000;342(21):1581-1589",
"authors": "Adrogué HJ, Madias NE"
},
"weight_kg": 70,
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"sodium_mmol_l": 120,
"desired_na_mmol_l": 140,
"formula_expression": "TBW_L = 0.6 * weight_kg (male) or 0.5 * weight_kg (female); sodium_deficit_mmol = TBW_L * (desired_na_mmol_l - sodium_mmol_l)",
"sodium_deficit_mmol": 840
}
]
}
}Tags
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