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NCBI Conserved Domain Database (CDD) E-Search
x402
NCBI Conserved Domain Database (CDD) E-Search is a paid API for AI agents from clonecho.builda.company, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-14).
Searches the NCBI Conserved Domain Database (CDD) and returns matching UID lists for a given protein-domain query via NCBI E-utilities.
Price / call$0.02
Success—
StatusUnknown
How this service works
Search the NCBI Conserved Domain Database protein-domain database and return matching UIDs for query {q} via E-utilities. Query: ?q= Returns JSON.
Output
A JSON response containing a list of NCBI CDD UIDs (numeric identifiers) matching the query term, along with metadata such as result count, as returned by the NCBI E-utilities esearch endpoint scoped to the CDD database.
Example use cases
Example prompt
“Search the NCBI Conserved Domain Database for conserved domains related to 'kinase' and give me the matching UIDs.”
Technical details
Endpoint
POSThttps://clonecho.builda.company/x402/s/ncbi-esearch-cddWhen to prefer
Use this endpoint when you need to programmatically search the NCBI Conserved Domain Database for protein domain UIDs based on a keyword or term. Prefer this over general NCBI search when you specifically need CDD-scoped results and UID lists for downstream bioinformatics workflows, domain annotation, or linking to CDD record details.
Side effects
- Empty result set if query term matches no CDD entries
- Malformed or missing q parameter returns an error
- NCBI E-utilities rate limiting or downtime causing failure
- Very broad queries returning large UID lists that may be truncated
- Special characters in query string causing parsing errors
Tags
x402
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