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NCBI dbSNP Variant Summary Lookup
x402
NCBI dbSNP Variant Summary Lookup is a paid API for AI agents from proxy.suverse.io, paid per call via x402, $0.002/call, status unknown (last checked 2026-09-14).
Fetches allele information and global minor allele frequencies for a given SNP rsID from NCBI dbSNP, aggregated across major reference studies like 1000 Genomes and ExAC.
Price / call$0.002
Success—
StatusUnknown
How this service works
Fetch dbSNP variant summary by rsID number: alleles and global minor allele frequencies across reference studies (1000 Genomes, ExAC, etc.). Keyless NCBI E-utilities. For agents querying SNP frequency data.
Output
Returns a variant summary for the queried rsID including the reference and alternate alleles, global minor allele frequency (MAF), and per-study minor allele frequencies from major reference panels such as 1000 Genomes, ExAC, and similar population genomics resources.
Example use cases
Pharmacogenomics variant frequency check
“What are the alleles and global minor allele frequency for rs1045642 — I need the breakdown from reference studies like 1000 Genomes and ExAC.”
APOE risk allele population frequency
“Look up the dbSNP summary for rs429358, including its alleles and how common the minor allele is across major population studies.”
MTHFR variant annotation pipeline
“I'm annotating a list of variants — can you fetch the allele frequencies and global MAF from dbSNP for rs1801133?”
Technical details
Endpoint
POSThttps://proxy.suverse.io/v1/data/suverse-bio-ncbi-snp-summaryWhen to prefer
Choose this endpoint when you need quick, keyless access to dbSNP variant summaries — specifically allele identities and global minor allele frequencies from reference studies — without managing NCBI API credentials. Ideal for bioinformatics agents, variant annotation pipelines, or pharmacogenomics workflows that need population frequency data on demand.
Side effects
- Invalid or non-existent rsID returns an error or empty result
- NCBI E-utilities rate limiting or downtime causes request failure
- Malformed request body (missing rsID field) returns a validation error
- SNP with no frequency data in reference studies returns partial or null MAF fields
- Payment failure (x402) prevents access to the endpoint
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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