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Pardanani 2018 MAPS Hybrid Prognostic Score for Systemic Mastocytosis
x402
Pardanani 2018 MAPS Hybrid Prognostic Score for Systemic Mastocytosis is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).
Calculates the Pardanani 2018 MAPS hybrid clinical-molecular prognostic score (Figure 3) for systemic mastocytosis, returning a numeric score and risk tier (Low/Intermediate-1/Intermediate-2/High).
Price / call$0.005
Success—
StatusUnknown
How this service works
Pardanani 2018 MAPS hybrid clinical-molecular (Figure 3): advanced SM 2 (ASM, SM-AHN, or MCL; ISM/SSM 0), age >60 1, platelets <150×10^9/L 1, ALP above UNL 1, ASXL1/RUNX1/NRAS 1; max 6. Low ≤2, intermediate-1 3, intermediate-2 4, high ≥5. Not WHO SM, not ICC SM, not clinical-only Figure 1. magent does not sequence, assay ALP, or count platelets.
Output
Returns the computed MAPS total score (integer 0-6), the corresponding risk tier label (Low ≤2, Intermediate-1 = 3, Intermediate-2 = 4, High ≥5), and per-variable point contributions based on Pardanani 2018 Figure 3.
Example use cases
Stratifying newly diagnosed ASM patient
“I have a 72-year-old patient with aggressive systemic mastocytosis, platelet count of 90, ALP that's above normal, and an NRAS mutation confirmed on sequencing — what's their MAPS score and risk tier?”
Prognostic scoring for SM-AHN workup
“Run the Pardanani MAPS score for a 55-year-old with SM-AHN: platelets are 200, ALP is within normal limits, no ASXL1/RUNX1/NRAS mutations found.”
Comparing indolent SM patient at risk boundary
“What does the MAPS hybrid score come out to for a 61-year-old with indolent SM, platelet count of 145, normal ALP, and no adverse mutations?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/mapsWhen to prefer
Use this endpoint when you need to apply the Pardanani 2018 MAPS hybrid clinical-molecular prognostic model (Figure 3) specifically — combining SM category, age, platelet count, ALP status, and ASXL1/RUNX1/NRAS mutation status. Prefer this over clinical-only or WHO/ICC-criteria-based tools when the hybrid score is explicitly required. Note: this endpoint does not perform sequencing, platelet counting, or ALP assay — callers must supply pre-determined values.
Side effects
- Invalid sm_category token (not 'indolent' or 'advanced') returns invalid_maps error
- Age outside 18-120 range causes validation failure
- Platelet count outside 1-2000 range causes validation failure
- Missing required query parameters returns 400-level error
- Caller-supplied clinical data that is inconsistent (e.g. platelets=0) may cause rejection
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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