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ROPE Score Calculator (Risk of Paradoxical Embolism)
x402
ROPE Score Calculator (Risk of Paradoxical Embolism) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Calculates the ROPE score (Kent 2013) to estimate the likelihood that a patent foramen ovale (PFO) is responsible for a cryptogenic stroke, based on age decade and five clinical flags.
Price / call$0.005
Success—
StatusUnknown
How this service works
ROPE (Risk of Paradoxical Embolism; Kent 2013 Neurology Table 4) from age decades (18-29 5, 30-39 4, 40-49 3, 50-59 2, 60-69 1, >=70 0) plus five caller-assigned 1-point factors (no hypertension, no diabetes, no prior stroke/TIA, nonsmoker, cortical infarct). Score 0-10 with abstract groupings 0-3, 4-8 residual, and 9-10. Not a PFO diagnosis, not a closure indication, not PASCAL. magent does not read imaging or a smoking history.
Output
Returns a ROPE score integer from 0 to 10 derived from age-decade points and five binary clinical flags, plus the abstract risk grouping (0–3, 4–8 residual, or 9–10) indicating how likely the patient's stroke is attributable to a PFO versus other causes.
Example use cases
Cryptogenic stroke PFO workup
“I have a 38-year-old cryptogenic stroke patient with no hypertension, no diabetes, no prior stroke or TIA, is a nonsmoker, and has a cortical infarct — can you calculate their ROPE score to see how attributable the PFO is?”
Elderly patient low ROPE expectation
“My patient is 72 years old, has hypertension and diabetes, has had a prior TIA, smokes, and has no cortical infarct — what is their ROPE score?”
Young nonsmoker high-score stratification
“Run the ROPE score for a 28-year-old with no hypertension, no diabetes, no prior stroke or TIA, who is a nonsmoker and does have a cortical infarct on imaging — I want to see which risk group they fall into.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/ropeWhen to prefer
Use this endpoint when you need a fast, deterministic ROPE score computation per Kent 2013 (Neurology) Table 4 for a cryptogenic stroke patient with known or suspected PFO. It is not a replacement for clinical imaging interpretation, PFO diagnosis, or closure indication assessment. Prefer this over manual arithmetic when integrating ROPE into automated clinical workflows or decision-support pipelines.
Side effects
- Missing any required query parameter (age, no_hypertension, no_diabetes, no_prior_stroke_tia, nonsmoker, cortical_infarct) returns an error
- Age below 18 or non-integer age value rejected
- Boolean flags supplied as non-boolean values cause validation error
- Payment failure or insufficient USDC balance returns 402 Payment Required
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"path": "/api/calc/rope",
"count": 2,
"items": [
{
"score": 0,
"formula": "rope",
"citation": {
"id": "kent-2013",
"doi": "10.1212/WNL.0b013e3182a08d59",
"pmid": "23864310",
"title": "An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke",
"source": "Neurology. 2013;81(7):619-625",
"authors": "Kent DM, Ruthazer R, Weimar C, Mas JL, Serena J, Homma S, Di Angelantonio E, Di Tullio MR, Lutz JS, Elkind MSV, Griffith J, Jaigobin C, Mattle HP, Michel P, Mono ML, Nedeltchev K, Papetti F, Thaler DE"
},
"age_years": 70,
"max_score": 10,
"components": [
{
"value": 70,
"factor": "age",
"points": 0,
"present": false
},
{
"factor": "no_hypertension",
"points": 0,
"present": false
},
{
"factor": "no_diabetes",
"points": 0,
"present": false
},
{
"factor": "no_prior_stroke_tia",
"points": 0,
"present": false
},
{
"factor": "nonsmoker",
"points": 0,
"present": false
},
{
"factor": "cortical_infarct",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"rope_stratum": "0_to_3",
"formula_expression": "ROPE = age_points + no_hypertension 1 + no_diabetes 1 + no_prior_stroke_tia 1 + nonsmoker 1 + cortical_infarct 1; age 18-29 5, 30-39 4, 40-49 3, 50-59 2, 60-69 1, >=70 0; Kent 2013 Table 4; max 10"
},
{
"score": 0,
"formula": "rope",
"citation": {
"id": "kent-2013",
"doi": "10.1212/WNL.0b013e3182a08d59",
"pmid": "23864310",
"title": "An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke",
"source": "Neurology. 2013;81(7):619-625",
"authors": "Kent DM, Ruthazer R, Weimar C, Mas JL, Serena J, Homma S, Di Angelantonio E, Di Tullio MR, Lutz JS, Elkind MSV, Griffith J, Jaigobin C, Mattle HP, Michel P, Mono ML, Nedeltchev K, Papetti F, Thaler DE"
},
"age_years": 70,
"max_score": 10,
"components": [
{
"value": 70,
"factor": "age",
"points": 0,
"present": false
},
{
"factor": "no_hypertension",
"points": 0,
"present": false
},
{
"factor": "no_diabetes",
"points": 0,
"present": false
},
{
"factor": "no_prior_stroke_tia",
"points": 0,
"present": false
},
{
"factor": "nonsmoker",
"points": 0,
"present": false
},
{
"factor": "cortical_infarct",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"rope_stratum": "0_to_3",
"formula_expression": "ROPE = age_points + no_hypertension 1 + no_diabetes 1 + no_prior_stroke_tia 1 + nonsmoker 1 + cortical_infarct 1; age 18-29 5, 30-39 4, 40-49 3, 50-59 2, 60-69 1, >=70 0; Kent 2013 Table 4; max 10"
}
]
}
}Tags
x402
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