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Sampson 2020 LDL-C Calculator
x402
Sampson 2020 LDL-C Calculator is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Estimates LDL cholesterol using the Sampson 2020 equation from total cholesterol, HDL, and triglycerides (valid up to 800 mg/dL triglycerides), in either mg/dL or mmol/L.
Price / call$0.005
Success—
StatusUnknown
How this service works
Sampson 2020 estimated LDL-C from total cholesterol, HDL, and triglycerides (valid through 800 mg/dL). One unit system (mg/dL or mmol/L). Deterministic published equation with citation; not Friedewald, not a diagnosis or statin order.
Output
Returns the estimated LDL-C value computed via the Sampson 2020 published equation, valid for triglycerides up to 800 mg/dL. Output is in the same unit system as the input (mg/dL or mmol/L). Includes the calculated LDL-C figure with citation context; not a diagnostic recommendation or statin guidance.
Example use cases
Lipid panel LDL estimation
“I have a patient's lipid panel: total cholesterol 240 mg/dL, HDL 45 mg/dL, triglycerides 300 mg/dL — can you use the Sampson 2020 equation to estimate their LDL-C?”
SI units LDL calculation
“Calculate the Sampson 2020 estimated LDL for these values in mmol/L: total cholesterol 6.2, HDL 1.4, triglycerides 2.1.”
High triglyceride LDL estimation
“My patient has very high triglycerides at 750 mg/dL, total cholesterol 310 mg/dL, and HDL 38 mg/dL — the Friedewald formula won't work here, can you use the Sampson 2020 method to estimate their LDL?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/sampsonWhen to prefer
Choose this endpoint when you need to estimate LDL-C from a standard lipid panel, especially when triglycerides are elevated (up to 800 mg/dL) where the Friedewald formula becomes unreliable. Prefer this over Friedewald-based calculators for patients with hypertriglyceridemia. Use when both mg/dL and mmol/L inputs are supported and you need a deterministic, citable published equation rather than a model-based estimate.
Side effects
- Triglycerides exceed 800 mg/dL — request rejected as outside equation validity range
- Mixed unit systems provided (some mg/dL, some mmol/L) — validation error
- Missing required lipid value (total cholesterol, HDL, or triglycerides) — parameter error
- Out-of-range values (e.g. HDL below 5 mg/dL or total cholesterol below 50 mg/dL) — rejected with range error
- Payment not provided or insufficient — x402 payment required response
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"path": "/api/calc/sampson",
"count": 2,
"items": [
{
"unit": "mg_dl",
"formula": "sampson",
"citation": {
"id": "sampson-2020",
"doi": "10.1001/jamacardiol.2020.0013",
"title": "A new equation for calculation of low-density lipoprotein cholesterol in patients with normolipidemia and/or hypertriglyceridemia",
"source": "JAMA Cardiol. 2020;5(5):540-548",
"authors": "Sampson M, Ling C, Sun Q, et al."
},
"hdl_mg_dl": 50,
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"ldl_c_mg_dl": 123.4,
"ldl_c_mmol_l": 3.2,
"formula_expression": "LDL-C = TC/0.948 - HDL/0.971 - (TG/8.56 + TG*(TC-HDL)/2140 - TG^2/16100) - 9.44 (mg/dL)",
"triglycerides_mg_dl": 150,
"total_cholesterol_mg_dl": 200
},
{
"unit": "mg_dl",
"formula": "sampson",
"citation": {
"id": "sampson-2020",
"doi": "10.1001/jamacardiol.2020.0013",
"title": "A new equation for calculation of low-density lipoprotein cholesterol in patients with normolipidemia and/or hypertriglyceridemia",
"source": "JAMA Cardiol. 2020;5(5):540-548",
"authors": "Sampson M, Ling C, Sun Q, et al."
},
"hdl_mg_dl": 50,
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"ldl_c_mg_dl": 123.4,
"ldl_c_mmol_l": 3.2,
"formula_expression": "LDL-C = TC/0.948 - HDL/0.971 - (TG/8.56 + TG*(TC-HDL)/2140 - TG^2/16100) - 9.44 (mg/dL)",
"triglycerides_mg_dl": 150,
"total_cholesterol_mg_dl": 200
}
]
}
}Tags
x402
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