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Simplified AIH Score Calculator (Hennes 2008)
x402
Simplified AIH Score Calculator (Hennes 2008) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Computes the Hennes 2008 simplified autoimmune hepatitis (AIH) score from caller-assigned autoantibody, IgG, histology, and viral hepatitis absence inputs, returning a total score and classification (not_aih / probable / definite).
Price / call$0.005
Success—
StatusUnknown
How this service works
Hennes 2008 simplified AIH (Table 2): caller-assigned autoantibody points 0-2 (max 2 across ANA/SMA/LKM/SLA), IgG points 0-2 (≤ULN / >ULN / >1.10×ULN), histology none 0 / compatible 1 / typical 2, viral hepatitis absent true 2. Max 8. Score <6 not_aih, 6 probable, ≥7 definite. Not a diagnosis and not the original 1999 IAHG score. magent does not titer autoantibodies, assay IgG vs ULN, or read liver histology.
Output
Returns the total simplified AIH score (integer 0–8) and a classification string: 'not_aih' for scores below 6, 'probable' for a score of 6, or 'definite' for scores of 7 or 8. Does not perform any laboratory interpretation itself — all four component point values must be pre-assigned by the caller.
Example use cases
Hepatology clinic AIH screening
“I have a patient with ANA ≥1:80 so autoantibody points are 2, IgG is just above the upper limit of normal so IgG points are 1, liver biopsy shows compatible histology, and viral hepatitis is absent — can you run the simplified AIH score and tell me if it's probable or definite?”
EHR automation pipeline scoring
“For this patient record: autoantibody points 1 (ANA 1:40), IgG points 0 (normal), histology none, and viral hepatitis not yet excluded — compute the Hennes 2008 simplified AIH score and classification.”
Differential diagnosis support
“Help me rule in or out autoimmune hepatitis: the patient has SLA positive so autoantibody points are 2, IgG points are 2 because IgG is more than 1.10 times ULN, histology is typical, and viral hepatitis is absent — what does the simplified AIH score say?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/simplified_aihWhen to prefer
Use this endpoint when an agent or workflow has already obtained and interpreted the four Hennes 2008 Table 2 criteria — autoantibody titer class, IgG-vs-ULN class, histology reading, and viral hepatitis serology result — and needs to convert them into a standardized total score and probable/definite/not_aih classification. Do not use if raw lab values (IgG concentration, antibody titers, histology slides, or viral serology) need to be interpreted; those steps must be done upstream. This is specifically the 2008 simplified score, not the original 1999 IAHG scoring system.
Side effects
- Missing required query parameters (autoantibody_points, igg_points, histology, viral_hepatitis_absent) returns a validation error
- Out-of-range integer values for autoantibody_points or igg_points (outside 0-2) are rejected
- Invalid histology enum value (must be 'none', 'compatible', or 'typical') returns an error
- Non-boolean value for viral_hepatitis_absent causes a schema validation failure
- Score does not constitute a clinical diagnosis; misuse of output without physician interpretation is a user-side failure
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"path": "/api/calc/simplified_aih",
"count": 2,
"items": [
{
"score": 8,
"formula": "simplified_aih",
"aih_band": "definite",
"citation": {
"id": "hennes-2008",
"doi": "10.1002/hep.22322",
"pmid": "18537184",
"title": "Simplified criteria for the diagnosis of autoimmune hepatitis",
"source": "Hepatology. 2008;48(1):169-176",
"authors": "Hennes EM, Zeniya M, Czaja AJ, Parés A, Dalekos GN, Krawitt EL, Bittencourt PL, Porta G, Boberg KM, Hofer H, Francesconi F, Dufour JF, Vergani D, Lohse AW; International Autoimmune Hepatitis Group"
},
"max_score": 8,
"components": [
{
"value": 2,
"factor": "autoantibody_points",
"points": 2,
"present": true
},
{
"value": 2,
"factor": "igg_points",
"points": 2,
"present": true
},
{
"value": "typical",
"factor": "histology",
"points": 2,
"present": true
},
{
"factor": "viral_hepatitis_absent",
"points": 2,
"present": true
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"formula_expression": "simplified AIH = autoantibody_points (0-2) + igg_points (0-2) + histology (none 0, compatible 1, typical 2) + viral_hepatitis_absent (true 2); Hennes 2008 Table 2; max 8; <6 not_aih, 6 probable, ≥7 definite"
},
{
"score": 8,
"formula": "simplified_aih",
"aih_band": "definite",
"citation": {
"id": "hennes-2008",
"doi": "10.1002/hep.22322",
"pmid": "18537184",
"title": "Simplified criteria for the diagnosis of autoimmune hepatitis",
"source": "Hepatology. 2008;48(1):169-176",
"authors": "Hennes EM, Zeniya M, Czaja AJ, Parés A, Dalekos GN, Krawitt EL, Bittencourt PL, Porta G, Boberg KM, Hofer H, Francesconi F, Dufour JF, Vergani D, Lohse AW; International Autoimmune Hepatitis Group"
},
"max_score": 8,
"components": [
{
"value": 2,
"factor": "autoantibody_points",
"points": 2,
"present": true
},
{
"value": 2,
"factor": "igg_points",
"points": 2,
"present": true
},
{
"value": "typical",
"factor": "histology",
"points": 2,
"present": true
},
{
"factor": "viral_hepatitis_absent",
"points": 2,
"present": true
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"formula_expression": "simplified AIH = autoantibody_points (0-2) + igg_points (0-2) + histology (none 0, compatible 1, typical 2) + viral_hepatitis_absent (true 2); Hennes 2008 Table 2; max 8; <6 not_aih, 6 probable, ≥7 definite"
}
]
}
}Tags
x402
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