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SYNTHORA PubMed E-utilities Search
x402
SYNTHORA PubMed E-utilities Search is a paid API for AI agents from pubmed-esearch.hergertsynthora.com, paid per call via x402, $0.001/call, status unknown (last checked 2026-09-13).
Searches PubMed's 37M+ biomedical citations via NCBI E-utilities esearch, returning matching PMIDs, result counts, and MeSH query translation as JSON
Price / call$0.001
Success—
StatusUnknown
How this service works
Searches PubMed's 37M+ biomedical citations via NCBI E-utilities esearch, returning matching PMIDs, result counts and MeSH query translation as JSON. Core keyless endpoint for autonomous biomedical research agents and agent-to-agent literature-triage pipelines needing a ranking surface over clinical and life-science literature. First 3 calls FREE per wallet — send header X-WALLET: 0x<addr>. No charge on upstream failure.
Output
A JSON object with an 'ok' boolean, a 'niche' field confirming 'pubmed-esearch', and a 'result' object containing the NCBI esearch response — including a list of matching PMIDs, the total count of results, and the MeSH-translated query string used by PubMed.
Example use cases
Drug interaction literature triage
“Search PubMed for all citations on metformin and lactic acidosis — I need the PMIDs, how many results there are, and the MeSH terms PubMed mapped my query to.”
Rare disease research discovery
“Can you query PubMed for papers about Niemann-Pick disease type C and return the list of PMIDs and total hit count so I can pull the full records next?”
Clinical agent literature pipeline
“Run a PubMed esearch for randomized controlled trials on cognitive behavioral therapy for treatment-resistant depression and give me the PMID list and MeSH query translation.”
Technical details
Endpoint
POSThttps://pubmed-esearch.hergertsynthora.com/serviceWhen to prefer
Choose this endpoint when you need fast, keyless programmatic access to PubMed's esearch functionality — especially in autonomous biomedical research agents or agent-to-agent literature-triage pipelines where you want PMIDs, result counts, and MeSH translation in a single JSON call without managing NCBI API credentials. Prefer it over direct NCBI API calls when operating in a microtransaction/x402 payment context or when routing through a standardized agent tool interface.
Side effects
- Empty result set if query terms are too specific or misspelled
- NCBI rate limiting or downtime causing upstream errors
- Malformed query string leading to zero results or API rejection
- Payment failure (x402) if USDC balance is insufficient
- Result object may be empty or partial if NCBI esearch returns an error code
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| query | string | query |
Output
Schema · Response
{
"type": "json",
"example": {
"ok": true,
"niche": "pubmed-esearch",
"result": {}
}
}Tags
x402
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