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Tisdale 2013 QT Prolongation Risk Score Calculator
x402
Tisdale 2013 QT Prolongation Risk Score Calculator is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).
Computes the Tisdale 2013 risk score for drug-induced QT prolongation and returns a risk band (low/moderate/high) based on nine clinical parameters.
Price / call$0.005
Success—
StatusUnknown
How this service works
Tisdale 2013 QT prolongation risk score (Table 5): age ≥68 (1), female (1), loop diuretic (1), potassium ≤3.5 mmol/L (2), admission QTc ≥450 ms (2), acute MI (2), sepsis (3), heart failure (3), one QTc-prolonging drug (3) plus ≥2 drugs (3 stacked; max 21). Returns bands 0-6 / 7-10 / ≥11. Deterministic published arithmetic with citation; not a medical device, not a drug-stop protocol, and not a TdP diagnosis.
Output
Returns the calculated Tisdale 2013 risk score (integer, maximum 21) and the corresponding risk band: low (0–6), moderate (7–10), or high (≥11), based on the sum of weighted clinical criteria from Table 5 of Tisdale 2013.
Example use cases
ICU sepsis patient on multiple QT drugs
“I need the Tisdale QT prolongation risk score for a 75-year-old male in the ICU with sepsis, heart failure, a QTc of 455 ms on admission, potassium of 3.4 mmol/L, on a loop diuretic, and currently receiving 3 QTc-prolonging drugs — no acute MI.”
Pre-prescribing safety check for azithromycin
“Before I add azithromycin, can you calculate the Tisdale 2013 QT risk score for this 65-year-old female patient? She has no sepsis, no MI, no heart failure, no loop diuretic, potassium is 4.0 mmol/L, admission QTc is 430 ms, and she's already on 1 QTc-prolonging drug.”
Elderly patient with hypokalemia and acute MI
“Run the Tisdale QT prolongation score for a 70-year-old male with an acute MI, potassium of 3.3 mmol/L, QTc of 470 ms at admission, on a loop diuretic, no sepsis, no heart failure, and currently on 1 QTc-prolonging medication.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/tisdaleWhen to prefer
Use this endpoint when you need a deterministic, published, citable arithmetic computation of the Tisdale 2013 QT prolongation risk score for a hospitalized patient. It is ideal for clinical decision-support agents that need to risk-stratify patients before initiating QTc-prolonging drugs, and when auditability via a published scoring table is required. It does not replace clinical judgment, diagnose TdP, or recommend drug changes.
Side effects
- Missing required query parameters returns a validation error
- Age outside 18–120 range is rejected
- Potassium outside 1.5–8.0 mmol/L is rejected
- QTc outside 200–800 ms is rejected
- qtc_prolonging_drugs count outside 0–20 is rejected
- Payment failure (x402) if USDC balance is insufficient
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Output
Schema · Response
{
"type": "json",
"example": {
"path": "/api/calc/tisdale",
"count": 2,
"items": [
{
"sex": "male",
"score": 0,
"formula": "tisdale",
"citation": {
"id": "tisdale-2013",
"doi": "10.1161/CIRCOUTCOMES.113.000152",
"pmid": "23716032",
"title": "Development and validation of a risk score to predict QT interval prolongation in hospitalized patients",
"source": "Circ Cardiovasc Qual Outcomes. 2013;6(4):479-487",
"authors": "Tisdale JE, Jaynes HA, Kingery JR, et al."
},
"age_years": 60,
"max_score": 21,
"components": [
{
"value": 60,
"factor": "age_ge_68",
"points": 0,
"present": false
},
{
"factor": "female",
"points": 0,
"present": false
},
{
"factor": "loop_diuretic",
"points": 0,
"present": false
},
{
"value": 4,
"factor": "potassium_le_3_5",
"points": 0,
"present": false
},
{
"value": 400,
"factor": "admission_qtc_ge_450",
"points": 0,
"present": false
},
{
"factor": "acute_mi",
"points": 0,
"present": false
},
{
"factor": "sepsis",
"points": 0,
"present": false
},
{
"factor": "heart_failure",
"points": 0,
"present": false
},
{
"value": 0,
"factor": "one_qtc_prolonging_drug",
"points": 0,
"present": false
},
{
"value": 0,
"factor": "two_or_more_qtc_prolonging_drugs",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"tisdale_band": "0-6",
"admission_qtc_ms": 400,
"potassium_mmol_l": 4,
"formula_expression": "Tisdale = age≥68 1 + female 1 + loop_diuretic 1 + potassium≤3.5 2 + admission_QTc≥450 2 + acute_MI 2 + sepsis 3 + heart_failure 3 + one_QTc_prolonging_drug 3 + ≥2_QTc_prolonging_drugs 3; Table 5; max 21; bands 0-6 / 7-10 / ≥11",
"qtc_prolonging_drugs": 0
},
{
"sex": "male",
"score": 0,
"formula": "tisdale",
"citation": {
"id": "tisdale-2013",
"doi": "10.1161/CIRCOUTCOMES.113.000152",
"pmid": "23716032",
"title": "Development and validation of a risk score to predict QT interval prolongation in hospitalized patients",
"source": "Circ Cardiovasc Qual Outcomes. 2013;6(4):479-487",
"authors": "Tisdale JE, Jaynes HA, Kingery JR, et al."
},
"age_years": 60,
"max_score": 21,
"components": [
{
"value": 60,
"factor": "age_ge_68",
"points": 0,
"present": false
},
{
"factor": "female",
"points": 0,
"present": false
},
{
"factor": "loop_diuretic",
"points": 0,
"present": false
},
{
"value": 4,
"factor": "potassium_le_3_5",
"points": 0,
"present": false
},
{
"value": 400,
"factor": "admission_qtc_ge_450",
"points": 0,
"present": false
},
{
"factor": "acute_mi",
"points": 0,
"present": false
},
{
"factor": "sepsis",
"points": 0,
"present": false
},
{
"factor": "heart_failure",
"points": 0,
"present": false
},
{
"value": 0,
"factor": "one_qtc_prolonging_drug",
"points": 0,
"present": false
},
{
"value": 0,
"factor": "two_or_more_qtc_prolonging_drugs",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"tisdale_band": "0-6",
"admission_qtc_ms": 400,
"potassium_mmol_l": 4,
"formula_expression": "Tisdale = age≥68 1 + female 1 + loop_diuretic 1 + potassium≤3.5 2 + admission_QTc≥450 2 + acute_MI 2 + sepsis 3 + heart_failure 3 + one_QTc_prolonging_drug 3 + ≥2_QTc_prolonging_drugs 3; Table 5; max 21; bands 0-6 / 7-10 / ≥11",
"qtc_prolonging_drugs": 0
}
]
}
}Tags
x402
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