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WHO 2016 Polycythemia Vera Diagnostic Criteria Calculator (Arber 2016)
x402
WHO 2016 Polycythemia Vera Diagnostic Criteria Calculator (Arber 2016) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).
Evaluates WHO 2016 (Arber 2016) polycythemia vera diagnostic criteria and returns whether the criteria are met based on caller-supplied hemoglobin, hematocrit, red-cell mass, bone marrow panmyelosis, JAK2 mutation status, and EPO findings.
Price / call$0.005
Success—
StatusUnknown
How this service works
WHO 2016 polycythemia vera criteria (Arber 2016). Met when all three majors hold, or when major 1 and major 2 hold with subnormal EPO. Major 1 is male Hb >16.5 g/dL or Hct >49%, female Hb >16.0 or Hct >48%, or increased red-cell mass. Major 2 is caller-assigned marrow panmyelosis. Major 3 is JAK2 V617F or exon 12. Not a medical device, not a WHO diagnosis, and not WHO 2022. magent does not assay EPO or sequence JAK2.
Output
Returns a structured result indicating whether the WHO 2016 (Arber 2016) polycythemia vera diagnostic criteria are met, which major criteria (1, 2, 3) were satisfied, whether the minor EPO criterion was triggered, and the overall diagnostic classification — without performing any laboratory assays itself.
Example use cases
Hematology EHR PV screening automation
“I have a female patient with hemoglobin 16.5 g/dL, hematocrit 49%, bone marrow panmyelosis confirmed, JAK2 V617F positive, and normal EPO — do the WHO 2016 Arber PV criteria say she has polycythemia vera?”
Two-major-criteria pathway with subnormal EPO
“This male patient has hemoglobin 17.0 g/dL, hematocrit 50%, no bone marrow biopsy done yet, JAK2 V617F positive, and subnormal EPO — can you run the WHO 2016 PV criteria check to see if the two-major plus minor path is satisfied?”
Increased red-cell mass pathway evaluation
“Patient has documented increased red-cell mass and confirmed bone marrow panmyelosis, JAK2 exon 12 mutation positive, sex is male, EPO is not subnormal — does this satisfy all three majors under WHO 2016 PV criteria?”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/who_pvWhen to prefer
Use this endpoint when you need to programmatically apply the WHO 2016 (Arber 2016) polycythemia vera criteria — not WHO 2022 — and all clinical findings (JAK2, bone marrow, EPO, hemoglobin/hematocrit) have already been determined by the clinician or lab. It is not a substitute for clinical judgment, molecular assay, pathology review, or EPO measurement. Prefer this over manual scoring when embedding PV criteria checking into an automated hematology workflow, EHR decision-support tool, or agentic clinical pipeline.
Side effects
- Missing required parameters (sex, bone_marrow_panmyelosis, jak2_v617f_or_exon12, subnormal_epo) returns a validation error
- No hemoglobin, hematocrit, or increased_red_cell_mass=true provided — at least one required, otherwise error
- Hemoglobin value outside valid range 3–22 g/dL returns an error
- Hematocrit value outside valid range 10–70% returns an error
- Payment not included or invalid x402 payment results in 402 response
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
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