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WPSS (WHO-based Prognostic Scoring System) Calculator for MDS
x402
WPSS (WHO-based Prognostic Scoring System) Calculator for MDS is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-13).
Computes the Malcovati 2007 WHO Prognostic Scoring System (WPSS) score and risk category for myelodysplastic syndromes from WHO MDS group, IPSS cytogenetic risk, and RBC transfusion status.
Price / call$0.005
Success—
StatusUnknown
How this service works
Malcovati 2007 WPSS for MDS: WHO category (RA/RARS/5q- 0, RCMD/RCMD-RS 1, RAEB-1 2, RAEB-2 3), IPSS karyotype (good 0, intermediate 1, poor 2; caller assigns the three-group class), regular RBC transfusion 1 (at least one every 8 weeks over 4 months); max 6. very_low 0 through very_high 5–6. Not IPSS-R, not IPSS 1997, not DIPSS. magent does not karyotype or assign WHO category.
Output
Returns the computed WPSS total score (integer 0–6) and the corresponding ordinal risk category label (very_low, low, intermediate, high, or very_high) based on Malcovati 2007 criteria. The caller is responsible for pre-assigning WHO MDS category and IPSS three-group cytogenetic class.
Example use cases
MDS prognosis at initial staging
“My newly diagnosed MDS patient has been classified as RAEB-1 by WHO criteria, has poor cytogenetics by IPSS three-group classification, and needs regular RBC transfusions every 8 weeks. What is their WPSS score and risk category?”
Low-risk MDS monitoring reassessment
“A patient with RA/RARS with isolated del(5q) has good cytogenetics and no regular transfusion requirement — can you run the WPSS to confirm their risk level is still very low?”
Transplant eligibility clinical decision
“We're evaluating a patient with RCMD-RS, intermediate cytogenetics by IPSS, and regular transfusion dependence for stem cell transplant — please compute their WPSS score to support the eligibility discussion.”
Technical details
Endpoint
GEThttps://api.magentlab.com/api/calc/wpssWhen to prefer
Use this endpoint when you need to apply the specific Malcovati 2007 WPSS system — not IPSS 1997 or IPSS-R — for MDS prognosis. The caller must have already assigned WHO 2001 MDS category and IPSS three-group cytogenetic risk externally; this endpoint handles only the arithmetic and risk-band classification. Prefer this over IPSS or IPSS-R calculators when the clinical context specifically requires WPSS, e.g. for longitudinal risk re-stratification or transfusion-weighted prognostication.
Side effects
- Missing required query parameter (who_mds, cytogenetics, or regular_transfusion) returns a validation error
- Invalid enum value for who_mds or cytogenetics (e.g. using IPSS-R five-group karyotype values like very_good or very_poor) returns an error
- Incorrect interpretation of cytogenetics scale (five-group IPSS-R vs. three-group IPSS 1997) may silently produce wrong scores
- Boolean parsing failure for regular_transfusion if not properly formatted
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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