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BIOS Deep Research Agent Analysis via x402
x402
BIOS Deep Research Agent Analysis via x402 is a paid API for AI agents from x402.ai.bio.xyz, paid per call via x402, $2/call, status unknown (last checked 2026-09-14).
Starts a paid AI deep-research analysis job on BIOS, settling USDC micropayment only upon job completion via the x402 protocol
Price / call$2
Success—
StatusUnknown
How this service works
Payment proxy for the BIOS Deep Research API, powered by the x402 protocol. This service wraps the BIOS deep-research endpoints with crypto micro-payments using USDC on Base. Payments are verified upfront but only settled once the research job completes. ## How it works 1. **Start a research job** — `POST /api/deep-research/start` with an x402 `PAYMENT-SIGNATURE` header. The payment is verified but not settled yet. 2. **Poll for results** — `GET /api/deep-research/{conversationId}` with an `X-SIWX` header (SIWE wallet signature). Only the wallet that paid can access results. 3. **On-demand settlement** — When polling a completed job, the payment is settled immediately and results returned. A background cron also handles batch settlement. 4. **Timeout handling** — If the payment window expires before completion, the conversation enters `timeout` status. A new payment is required to retrieve results. ## SIWX Authentication (Sign-In With X) The `GET /api/deep-research/{conversationId}` endpoint requires wallet-based authentication via EIP-4361 (SIWE). When called without a valid `X-SIWX` header, the endpoint returns `401` with a SIWE challenge. The client must sign this challenge with the same wallet that made the original payment and resend the request. The `X-SIWX` header is a base64-encoded JSON object: `{ "message": "<EIP-4361 message>", "signature": "0x..." }`. ## x402 Payment Protocol All paid endpoints return `402 Payment Required` with a `PAYMENT-REQUIRED` header when no payment is provided. The header contains the payment requirements (price, token, network) that clients use to construct a payment. See [x402 docs](https://docs.cdp.coinbase.com/x402/core-concepts/how-it-works) for details.
Output
Returns a JSON object with a 'status' field (e.g. 'queued') and a 'taskId' (e.g. 'task_abc123') that can be used to poll for results via the GET endpoint once the research job completes.
Example use cases
Biomedical literature deep dive
“Run a BIOS deep research analysis asking 'What are the most promising mRNA vaccine targets for pancreatic cancer as of 2024?' and pay the $2 USDC fee from my wallet.”
Drug mechanism investigation
“I need a thorough AI research report on how GLP-1 receptor agonists affect neuroinflammation — kick off a BIOS deep research job on that topic and handle the micropayment.”
Competitive biotech landscape analysis
“Use BIOS to do a deep research analysis on the current competitive landscape for CRISPR therapeutics companies, paying the $2 fee via my Base wallet.”
Technical details
Endpoint
POSThttps://x402.ai.bio.xyz/api/agents/analysis/runWhen to prefer
Choose this endpoint when you need a comprehensive, AI-driven deep-research analysis on a complex topic (especially biomedical or scientific) and are willing to pay $2 USDC per job via the x402 crypto micropayment protocol on Base. Prefer this over general web search or simple LLM queries when depth, synthesis, and structured research output matter. It is ideal for agentic workflows where you want verifiable, pay-per-use research without a subscription.
Side effects
- Invalid or missing x402 PAYMENT-SIGNATURE header — payment verification fails, job not started
- Insufficient USDC balance on Base — payment rejected before job is queued
- Payment window times out before research completes — conversation enters 'timeout' status, new payment required
- Malformed research query — may result in job error or poor-quality output
- Network errors on Base blockchain during payment verification — request fails
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| fileIds | array | Optional file IDs (from POST /api/files/upload) to include in the analysis |
| taskDescription | string | Description of the analysis task to perform |
Output
Schema · Response
{
"type": "json",
"example": {
"status": "queued",
"taskId": "task_abc123"
}
}Tags
x402
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