10 Services from bio.halowerk.com

Ranks user-supplied candidate protospacers against a guide RNA sequence using a mismatch-weighted similarity score with NGG PAM penalty, emphasizing the guide's seed region (final 10 positions).

Standardizes caller-supplied biomarker values against provided reference means and standard deviations, flips markers where lower is better, and computes a weighted composite score mapped to a 0–100 index.

Normalizes taxon counts and computes observed richness, Shannon entropy, Simpson diversity, and Pielou evenness from caller-supplied species count data

Validates a 2D hydrophobic/polar (HP) lattice conformation and computes its energy by counting non-consecutive hydrophobic contacts, assigning -1 energy unit per contact.

Computes theoretical maximum product yield from multiple substrates by identifying the limiting substrate and applying a process efficiency factor.

Computes a basic reproduction number (R0) and effective reproduction number (Re) using a simple homogeneous-mixing formula from transmission probability, contact rate, and infectious duration.

Slides each caller-supplied CRISPR spacer over a phage sequence in both orientations and reports minimum Hamming distances within a caller-selected mismatch threshold

Encodes UTF-8 text into a DNA nucleotide string by mapping each two-bit group to A, C, G, or T, and returns a SHA-256 checksum of the original bytes.

Builds amino-acid k-mer sets from a query protein sequence and known epitopes, computes Jaccard similarity, and finds the highest contiguous identity window between each epitope and the query sequence.

Computes fluid permeability and flow rate through a porous tissue scaffold using the Kozeny-Carman relation and Darcy's law given porosity, pore diameter, thickness, viscosity, and pressure drop.